2-Bromo-3-(4,4-difluoropiperidin-1-yl)pyridine CAS 1707581-05-2
| CAS No. | 1707581-05-2 |
| Molecular Formula | C10H11BrF2N2 |
| Molecular Weight | 277.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Bromo-3-(4,4-difluoropiperidin-1-yl)pyridine (CAS 1707581-05-2), molecular formula C10H11BrF2N2 and molecular weight 277.11 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-3-(4,4-difluoropiperidin-1-yl)pyridine (C10H11BrF2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H11BrF2N2 |
| Molecular Weight | 277.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-bromo-4-phenoxybenzaldehyde (CAS 1000414-11-8)
- 2-Bromo-[1,1'-biphenyl]-3-carboxylic acid (CAS 1049143-36-3)
- 2-Bromo-1,4-bis(methoxymethoxy)benzene (CAS 131136-47-5)
- methyl 6-bromo-3-oxo-benzofuran-2-carboxylate (CAS 1403582-72-8)
- 3-Bromo-5-(3,3-difluoropyrrolidin-1-ylmethyl)-pyridine (CAS 1428065-38-6)
- 3-Bromo-5-(4,4-difluoropiperidin-1-yl)pyridine (CAS 1707358-05-1)
- 3-Bromo-4-(3,3-difluoropiperidin-1-yl)pyridine (CAS 1707358-06-2)
- 1707365-66-9 3-Bromo-4-(4,4-difluoropiperidin-1-yl)pyridine (CAS 1707365-66-9)
Recommended Standards
- 3-Bromo-5-(3,3-difluoropiperidin-1-yl)pyridine (CAS 1707365-68-1)
- 4-Bromo-3-(4,4-difluoropiperidin-1-yl)pyridine (CAS 1707581-06-3)
- 4-Bromo-3-(3,3-difluoropiperidin-1-yl)pyridine (CAS 1713160-13-4)
- 2-Bromo-4-(3,3-difluoropiperidin-1-yl)pyridine (CAS 1713160-15-6)
- Methyl 2,5-dibromonicotinate (CAS 78686-82-5)
- 4,5,6,7-Tetrahydro-1H-benzo[d][1,2,3]triazole-6-carboxylic acid (CAS 33062-47-4)
- (2-Methoxy-5-nitrophenyl)methanol (CAS 5804-49-9)
- N-(4-(Trifluoromethyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1021219-52-2)
- 2-Amino-4’-bromobenzophenone (CAS 1140-17-6)
- 4,6-Dichloro-2-isobutylpyrimidin-5-amine (CAS 61457-01-0)
- 3-Amino-6-iodopyrazine-2-carboxamide (CAS 1244949-61-8)
- 3-(4-(Cyanomethoxy)-3-methoxyphenyl)acrylic acid (CAS 565191-96-0)
- 3-Amino-3-methyl-1-pentyne Hydrochloride (CAS 108575-32-2)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com