2-Amino-5-(ethylsulfonyl)-4-(o-tolyl)thiophene-3-carbonitrile CAS 1708269-25-3
| CAS No. | 1708269-25-3 |
| Molecular Formula | C14H14N2O2S2 |
| Molecular Weight | 306.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Amino-5-(ethylsulfonyl)-4-(o-tolyl)thiophene-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Amino-5-(ethylsulfonyl)-4-(o-tolyl)thiophene-3-carbonitrile (CAS 1708269-25-3) is a high-purity analytical reference standard with the molecular formula C14H14N2O2S2 and a molecular weight of 306.40 g/mol.
The molecular framework of 2-Amino-5-(ethylsulfonyl)-4-(o-tolyl)thiophene-3-carbonitrile (C14H14N2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14N2O2S2 |
| Molecular Weight | 306.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Amino Standards
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- 4-(4-Amino-2-methyl-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester (CAS 138227-69-7)
- 2-Amino-5-(ethylsulfonyl)-4-(p-tolyl)thiophene-3-carbonitrile (CAS 1708444-81-8)
- 2-Amino-5-(ethylsulfonyl)-4-(m-tolyl)thiophene-3-carbonitrile (CAS 1710833-66-1)
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Recommended Standards
- Tert-butyl 4-((pyrimidin-5-ylmethyl)amino)azepane-1-carboxylate (CAS 1699521-51-1)
- Tert-butyl (5-(azepan-4-ylamino)pyridin-2-yl)carbamate (CAS 1699251-73-4)
- tert-Butyl ((4-benzylmorpholin-3-yl)methyl)carbamate (CAS 169750-74-7)
- Tert-butyl 4-amino-4-(3-methoxyphenyl)piperidine-1-carboxylate (CAS 1774905-33-7)
- Ruthenium, trichloro[1,1'-thiobis[ethane]]- (CAS 68630-81-9)
- N,N'-(6-((6-Aminohexyl)amino)-6-oxohexane-1,5-diyl)bis(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide) 2,2,2-trifluoroacetate (CAS 1301738-40-8)
- 2-Methylhexahydro-1H-pyrazino[1,2-c]pyrimidin-6(2H)-one (CAS 151733-63-0)
- N-[(4-fluorophenyl)methyl]hydroxylamine (CAS 116250-34-1)
- 1,1'-(Methylenebis(2,4-dihydroxy-6-methoxy-3,1-phenylene))bis(ethan-1-one) (CAS 142382-28-3)
- 4-Bromo-2-formylphenyl 4-methoxybenzoate (CAS 443736-82-1)
- Methyl 3-(3-fluorophenyl)propanoate (CAS 425704-52-5)
- 2,6-Dimethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 214360-59-5)
- 3-Methyl-4-phenoxy-1-(pyridin-2-yl)-1H-pyrazol-5(4H)-one (CAS 111987-97-4)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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