7-(Piperazin-1-yl)-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine CAS 1708427-91-1
| CAS No. | 1708427-91-1 |
| Molecular Formula | C10H11F3N6 |
| Molecular Weight | 272.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 7-(Piperazin-1-yl)-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 272.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
7-(Piperazin-1-yl)-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1708427-91-1) is a high-purity analytical reference standard with the molecular formula C10H11F3N6 and a molecular weight of 272.23 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11F3N6 |
| Molecular Weight | 272.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Piperazin Standards
- (4-Piperazin-1-ylphenyl)(2-thienyl)methanone (CAS 725720-16-1)
- 1-Ethyl-3-(piperazin-1-ylmethyl)quinolin-2(1H)-one (CAS 1437435-80-7)
- 2-(3-(Piperazin-1-yl)propyl)isoindoline-1,3-dione (CAS 1000547-80-7)
- (4-(Piperazin-1-yl)-2-(trifluoromethyl)phenyl)boronic acid (CAS 2225169-50-4)
- 1-Benzyl-3-(piperazin-1-yl)pyrazin-2(1H)-one (CAS 1707571-47-8)
- 2-(4-Methyl-6-(piperazin-1-yl)pyrimidin-2-yl)phenol (CAS 330982-03-1)
- 2-(Piperazin-1-ylsulfonyl)benzoic acid (CAS 1215613-85-6)
- (3-(Piperazin-1-ylsulfonyl)phenyl)boronic acid (CAS 1704063-60-4)
Recommended Standards
- 1-(5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-3-amine (CAS 1708268-21-6)
- 1-(2-Fluorophenyl)-5-(1H-pyrrol-1-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1710845-82-1)
- 3-(Difluoromethyl)-5-((4-nitrophenyl)thio)-4H-1,2,4-triazole (CAS 1706447-94-0)
- m-PEG4-phosphonic acid (CAS 1872433-62-9)
- 3,5-Dimethyl-4-phenyl-1H-pyrazole (CAS 4345-49-7)
- (3-(4-(Aminomethyl)cyclohexyl)benzo[b]thiophen-2-yl)(morpholino)methanone hydrochloride (CAS 1361111-26-3)
- Ethyl 4-chloro-1,5-naphthyridine-3-carboxylate (CAS 83067-95-2)
- Oxaliplatin EP Impurity B (CAS 89955-85-1)
- (5E)-5-(3-Isopropoxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one 127378-77-2 3441AD C13H13NO2S2 (CAS 127378-77-2)
- [1-(2-aminopyrimidin-4-yl)pyrrolidin-2-yl]methanol (CAS 1533543-04-2)
- 3-(2,2,3,3,3-pentafluoropropoxy)propanoic acid (CAS 1603018-94-5)
- 3-(4-(Tert-butyl)phenyl)-3-methylbutanoic acid (CAS 42288-09-5)
- 3-(3-Methoxyphenyl)-3,4,5-trifluoropropiophenone (CAS 898775-37-6)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
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