5-[4-(2,4-Difluorophenyl)Phenyl]-5-Hydroxy-3-Methylfuran-2-One CAS 170950-57-9
| CAS No. | 170950-57-9 |
| Molecular Formula | C17H12F2O3 |
| Molecular Weight | 302.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-[4-(2,4-Difluorophenyl)Phenyl]-5-Hydroxy-3-Methylfuran-2-One (C17H12F2O3) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 302.27 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-[4-(2,4-Difluorophenyl)Phenyl]-5-Hydroxy-3-Methylfuran-2-One (CAS 170950-57-9) is a high-purity analytical reference standard with the molecular formula C17H12F2O3 and a molecular weight of 302.27 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-[4-(2,4-Difluorophenyl)Phenyl]-5-Hydroxy-3-Methylfuran-2-One meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H12F2O3 |
| Molecular Weight | 302.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
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- N4-(3,4-Difluorophenyl)-7-methoxyquinazoline-4,6-diamine (Dacomitinib Impurity) (CAS 2117703-26-9)
- 1-(2,4-Difluorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-78-5)
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Recommended Standards
- 4-(2',4'-Difluoro-[1,1'-biphenyl]-4-yl)-2-methylene-4-oxobutanoic acid (CAS 161692-81-5)
- 4-Phenylphenyl triflate (CAS 17763-78-9)
- 5-Methyl-2-((2-(trifluoromethyl)phenyl)amino)thiazole-4-carboxylic acid (CAS 1553555-69-3)
- Ethyl 5-(2-triflluoromethylphenyl)-1,3,4-thiadiazole-2-carboxylate (CAS 1924322-02-0)
- 4-Chloro-5-phenylpyrimidine (CAS 60122-80-7)
- 3-(3-tert-Butoxy-3-oxo-2-palmitamidopropylthio)-propane-1,2-diyl dipalmitate (CAS 87363-03-9)
- 4,4,5,5-Tetramethyl-2-(2,4,6-trifluorophenyl)-1,3,2-dioxaborolane (CAS 325143-04-2)
- 2,2,2-Trifluoro-1-(1-phenylcyclopropyl)ethan-1-ol (CAS 2091544-94-2)
- ((R)-3-Benzyloxycarbonylamino-piperidin-1-yl)-acetic acid (CAS 1354016-38-8)
- (4-Ethoxy-2-methoxyphenyl)boronic acid (CAS 1207443-48-8)
- Ipratropium Bromide Impurity 36 (CAS CATO-C4X-166536)
- Nitrofluorfen (CAS 42874-01-1)
- Benzyl 2-(6-amino-2-methylpyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352499-46-7)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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