4-(4-Chlorophenyl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine CAS 1713174-46-9
| CAS No. | 1713174-46-9 |
| Molecular Formula | C12H10ClN3O2S2 |
| Molecular Weight | 327.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Chlorophenyl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1713174-46-9), molecular formula C12H10ClN3O2S2 and molecular weight 327.81 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(4-Chlorophenyl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (C12H10ClN3O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 327.81 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Chlorophenyl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN3O2S2 |
| Molecular Weight | 327.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 2-(3-(1-(4-Chlorophenyl)cyclopropyl)-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propan-2-ol (CAS 1140897-32-0)
- 4-(3-Chlorophenyl)-5-(methylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1708289-19-3)
- 1-{[4-(3-chlorophenyl)piperazino]methyl}-1H-1,2,3-benzotriazole (CAS 301194-17-2)
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Recommended Standards
- Loxapine (CAS 1977-10-2)
- (S)-1'-(tert-butyl)-3-chloro-5,7-dihydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one (CAS 1455358-14-1)
- (Z)-3-(5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid (CAS 7177-97-1)
- 3-(2-Chloro-8-methylquinolin-3-yl)-5-cyclohexyl-1,2,4-oxadiazole (CAS 1431728-51-6)
- 2-(Aminomethyl)cyclopropaneacetonitrile (CAS 2409826-83-9)
- N-(2-hydroxyethyl)-4-iodobenzamide (CAS 57728-65-1)
- Ethyl 2-amino-5-(trifluoromethyl)isonicotinate (CAS 1227575-40-7)
- Ethyl 2-(2-chlorophenyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1332506-36-1)
- (3R,4S,5R)-4-Hydroxy-5-[(1S)-1-hydroxy-2-methylpropyl]-3-methyl-2-pyrrolidinone-5-carboxylic Acid (CAS 145451-97-4)
- tert-Butyl 3-(3-oxopropyl)azetidine-1-carboxylate (CAS 154748-55-7)
- 3,4-Dihydroquinoline-1(2H)-carbonyl chloride (CAS 2616-50-4)
- Ceritinib Impurity 58 (CAS CATO-C4X-104858)
- 1,10-phenanthroline hydrochloride monohydrate (CAS 18851-33-7)
- Peptide T (CAS 106362-32-7)
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