4-Chloro-5-fluoro-1H-indazol-3-amine CAS 1715913-00-0
| CAS No. | 1715913-00-0 |
| Molecular Formula | C7H5ClFN3 |
| Molecular Weight | 185.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Chloro-5-fluoro-1H-indazol-3-amine (CAS 1715913-00-0), molecular formula C7H5ClFN3 and molecular weight 185.59 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-5-fluoro-1H-indazol-3-amine (C7H5ClFN3) is characterized by a nitrile group, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Chloro-5-fluoro-1H-indazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClFN3 |
| Molecular Weight | 185.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-chloro-6-fluoro-1H-benzo[d]imidazol-5-amine (CAS 117275-51-1)
- 5-Chloro-7-fluoro-1H-benzo[d]imidazol-6-amine (CAS 1426290-07-4)
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- 3-Chloro-4-fluoro-1H-indazol-6-amine (CAS 885520-15-0)
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