Iodixanol EP Impurity G CAS 171897-72-6
| CAS No. | 171897-72-6 |
| Molecular Formula | C35H43I5N6O15 |
| Molecular Weight | 1422.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Iodixanol EP Impurity G (CAS 171897-72-6, C35H43I5N6O15) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Iodixanol EP Impurity G (C35H43I5N6O15) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 1422.27 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Iodixanol EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C35H43I5N6O15 |
| Molecular Weight | 1422.27 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 6 |
Related Iodixanol Standards
- Iodixanol Impurity 11 (CAS CATO-C4X-166311)
- Iodixanol Impurity 10 (CAS CATO-C4X-166310)
- Iodixanol EP Impurity F (CAS 171897-73-7)
- Iodixanol EP Impurity E (CAS 255376-57-9)
- Iodixanol EP Impurity C (CAS 171897-74-8)
- Iodixanol (CAS 92339-11-2)
- Iodixanol EP Impurity I (CAS CATO-C4X-16639)
- Iodixanol USP Related Compound D (CAS 89797-00-2)
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