Revefenacin impurity 30 CAS 1719-82-0
| CAS No. | 1719-82-0 |
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Revefenacin impurity 30 (CAS 1719-82-0, C10H12O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Revefenacin impurity 30 (C10H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12O3 |
| Molecular Weight | 180.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Revefenacin Standards
- Revefenacin impurity 87 (CAS CATO-C4X-203187)
- Revefenacin impurity 31 (CAS CATO-C4X-203131)
- Revefenacin Impurity 26 (CAS 108015-71-0)
- Revefenacin Impurity 113 (CAS 1379371-59-1)
- Revefenacin impurity 94 (CAS CATO-C4X-203194)
- Revefenacin impurity 97 (CAS 774238-89-0)
- Revefenacin impurity 90 (CAS CATO-C4X-203190)
- Revefenacin impurity 92 (CAS CATO-C4X-203192)
Recommended Standards
- 4-Propoxybenzoic Acid (CAS 5438-19-7)
- Neostigmine Impurity 26 (CAS 4849-46-1)
- Methoxamine Impurity 9 (CAS 49710-99-8)
- Neostigmine impurity 37 (CAS CATO-C4X-204237)
- Ergosterol Impurity 9 (CAS 71075-32-6)
- S-Adenosyl-L-Methionine Impurity 7 (CAS CATO-C4X-13817)
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- 5-Bromo-2-fluoroisonicotinaldehyde (CAS 1227588-77-3)
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