(Z)-3-((Benzylamino)methylene)-1-(2,6-dichlorophenyl)indolin-2-one CAS 172371-92-5
| CAS No. | 172371-92-5 |
| Molecular Formula | C22H16Cl2N2O |
| Molecular Weight | 395.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (Z)-3-((Benzylamino)methylene)-1-(2,6-dichlorophenyl)indolin-2-one (C22H16Cl2N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(Z)-3-((Benzylamino)methylene)-1-(2,6-dichlorophenyl)indolin-2-one (CAS 172371-92-5) is a high-purity analytical reference standard with the molecular formula C22H16Cl2N2O and a molecular weight of 395.28 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (Z)-3-((Benzylamino)methylene)-1-(2,6-dichlorophenyl)indolin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl2N2O |
| Molecular Weight | 395.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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