4-Bromo-5-(methylsulfonyl)thiophene-2-carboxylic acid CAS 172461-97-1
| CAS No. | 172461-97-1 |
| Molecular Formula | C6H5BrO4S2 |
| Molecular Weight | 285.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Bromo-5-(methylsulfonyl)thiophene-2-carboxylic acid (CAS 172461-97-1), a certified reference material (molecular formula C6H5BrO4S2, MW 285.14 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromo-5-(methylsulfonyl)thiophene-2-carboxylic acid (C6H5BrO4S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Bromo-5-(methylsulfonyl)thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5BrO4S2 |
| Molecular Weight | 285.14 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 2 |
Related Bromo Standards
- 6-Bromo-2-phenylquinazoline (CAS 1004997-72-1)
- 6-Bromo-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol (CAS 1005490-98-1)
- 4-Bromo-N-cyclopentyl-2-nitroaniline (CAS 1036585-23-5)
- 5-Bromo-1-(2,2-dimethoxyethyl)-1H-indazole (CAS 1039826-68-0)
- 1-(6-Bromo-2-pyridinyl)-4-piperidinecarboxylic acid (CAS 1065484-33-4)
- 3-Bromo-4-piperazinobenzoic Acid (CAS 1131594-67-6)
- 1147447-05-9 4-(5-Bromo-pyridin-2-yl)-isoquinoline MFCD13152529 (CAS 1147447-05-9)
- 4-Bromo-2-piperazinobenzoic Acid (CAS 1197193-25-1)
Recommended Standards
- 4,5-Dichloro-3-(2-ethoxyethoxy)thiophene-2-carboxylic acid (CAS 1708251-09-5)
- 5-Bromo-3-(2-(dimethylamino)ethyl)benzo[d]oxazol-2(3H)-one (CAS 1802149-27-4)
- 5-Bromo-N-(cyclopropylmethyl)-2-methoxynicotinamide (CAS 1708250-62-7)
- 1-(5-Bromopyridin-3-yl)piperidine-4-carboxylic acid (CAS 1823511-42-7)
- 5-(2-Fluoroethoxy)pyrazine-2-carboxylic acid (CAS 1174323-42-2)
- 1,4,5-Triamino-2,6-bis(3,4-dichlorophenoxy)anthracene-9,10-dione (CAS 88600-54-8)
- N-(sec-Butyl)cyclohexanamine (CAS 42966-62-1)
- methyl 2-(thietan-3-ylidene)acetate (CAS 61890-04-8)
- 6-Fluoro-5-methyl-1H-indole (CAS 162100-95-0)
- Cycloheptanecarboxamide (CAS 1459-39-8)
- 1-Phenyl-1H-pyrazol-3-ylamine (CAS 1128-56-9)
- 5-(Dimethylphosphoryl)-2-hydroxybenzamide (CAS 2903924-05-8)
- benzyl benzyl((1R,2R)-2-hydroxycyclohexyl)carbamate (CAS 906802-32-2)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com