Diazepam Impurity 9 CAS 17247-17-5
| CAS No. | 17247-17-5 |
| Molecular Formula | C16H12Cl3NO2 |
| Molecular Weight | 356.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H12Cl3NO2, Diazepam Impurity 9 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Diazepam Impurity 9 (CAS 17247-17-5) is a certified pharmaceutical impurity reference standard with the molecular formula C16H12Cl3NO2 and a molecular weight of 356.63 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Diazepam Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl3NO2 |
| Molecular Weight | 356.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 2-(3-Chlorophenyl)-6-methylpyrimidine-4(3H)-thione (CAS 1239759-77-3)
- 2-(Methylamino)-N-(prop-2-yn-1-yl)benzamide (CAS 35727-71-0)
- 5-(5-Chloropentyl)-3-methylimidazo[1,5-a]pyridine (CAS 85691-41-4)
- Granisetron EP Impurity F (CAS 1364914-39-5(free base))
- 2,6-Dichloro-3-fluorobenzyl chloride (CAS 1806354-44-8)
- Peptide 436 (CAS CATO-CPTD788436)
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