2-Chloro-5-methylthiophene CAS 17249-82-0
| CAS No. | 17249-82-0 |
| Molecular Formula | C5H5ClS |
| Molecular Weight | 132.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-methylthiophene (CAS 17249-82-0), molecular formula C5H5ClS and molecular weight 132.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to sulfur-containing functionality, chlorine substitution, 2-Chloro-5-methylthiophene is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 132.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-5-methylthiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5ClS |
| Molecular Weight | 132.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-3-methylthiophene (CAS 14345-97-2)
- 3-Chloro-2-methylthiophene (CAS 17249-83-1)
- 2-Chloro-4-methylthiophene (CAS 91505-25-8)
- 4-Chloro-2-methylthiophene (CAS 91375-70-1)
- 5-chloro-5-methylhex-1-ene (CAS 116911-84-3)
- 6-Chloro-5-methylhex-1-ene (CAS 1342612-45-6)
- 1-Chloro-1-methylcyclohexane (CAS 931-78-2)
- 1-Chloro-3-ethylpent-2-ene (CAS 761-20-6)
Recommended Standards
- 1134E5H2KV 822-87-7 2-Chlorocyclohexanone Cyclohexanone, 2-chloro- alpha-Chlorocyclohexanone 2-Chlorocyclohexonone EINECS 212-505-5 NSC 12439 UNII-1134E5H2KV (CAS 822-87-7)
- Hex-5-enoyl chloride (CAS 36394-07-7)
- 2-Chloromethylthiophene (CAS 765-50-4)
- Cyclopentanecarbonyl Chloride (CAS 4524-93-0)
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- 2-Amino-5-fluoro-4-iodopyridine (CAS 1649470-53-0)
- D-Gln19-Tirzepatide (CAS CATO-CPTD788915)
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