3-(1,3-Dioxoisoindolin-2-yl)-N,N-dimethylpropanamide CAS 17268-46-1
| CAS No. | 17268-46-1 |
| Molecular Formula | C13H14N2O3 |
| Molecular Weight | 246.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(1,3-Dioxoisoindolin-2-yl)-N,N-dimethylpropanamide (CAS 17268-46-1) is a high-purity analytical reference standard with the molecular formula C13H14N2O3 and a molecular weight of 246.26 g/mol.
The molecular framework of 3-(1,3-Dioxoisoindolin-2-yl)-N,N-dimethylpropanamide (C13H14N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(1,3-Dioxoisoindolin-2-yl)-N,N-dimethylpropanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O3 |
| Molecular Weight | 246.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
Related Dioxoisoindolin Standards
- N-(1,3-Dioxoisoindolin-5-yl)-3-oxobutanamide (CAS 68093-84-5)
- (R)-2-(1,3-dioxoisoindolin-2-yl)-3-methylbutanoic acid (CAS 6306-53-2)
- 1,3-Dioxoisoindolin-2-yl pivalate (CAS 84379-72-6)
- 2-(1,3-Dioxoisoindolin-2-yl)-3-methylbutanoic acid (CAS 5115-65-1)
- 4-(5-Methyl-1,3-dioxoisoindolin-2-yl)butanoic acid (CAS 346704-25-4)
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