(R)-8-(Benzyloxy)-5-(2-chloro-1-hydroxyethyl)quinolin-2(1H)-one CAS 172967-64-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-8-(Benzyloxy)-5-(2-chloro-1-hydroxyethyl)quinolin-2(1H)-one.

(R)-8-(Benzyloxy)-5-(2-chloro-1-hydroxyethyl)quinolin-2(1H)-one (CAS 172967-64-5), molecular formula C18H16ClNO3 and molecular weight 329.78 g/mol, is a CATO reference standard with documented purity and traceability.

(R)-8-(Benzyloxy)-5-(2-chloro-1-hydroxyethyl)quinolin-2(1H)-one (C18H16ClNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-8-(Benzyloxy)-5-(2-chloro-1-hydroxyethyl)quinolin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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