4-(4-Trifluoromethoxyphenyl)phenol CAS 173025-79-1
| CAS No. | 173025-79-1 |
| Molecular Formula | C13H9F3O2 |
| Molecular Weight | 254.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Trifluoromethoxyphenyl)phenol (CAS 173025-79-1), molecular formula C13H9F3O2 and molecular weight 254.20 g/mol, is a CATO reference standard with documented purity and traceability.
4-(4-Trifluoromethoxyphenyl)phenol (C13H9F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9F3O2 |
| Molecular Weight | 254.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | F-containing |
Related Trifluoromethoxyphenyl Standards
- 4-(3-Trifluoromethoxyphenyl)benzoic Acid (CAS 1093758-81-6)
- 4-(4-Trifluoromethoxyphenyl)benzoic acid (CAS 728919-11-7)
- 3-(4-Trifluoromethoxyphenyl)Isonicotinic acid (CAS 1261783-07-6)
- 3-Methyl-4-(4-trifluoromethoxyphenyl)benzoic acid (CAS 1261560-31-9)
- 2-(4-Trifluoromethoxyphenyl)-4-(3-pyridyl)thiazole (CAS 1965305-03-6)
- Ethyl 2-(4-trifluoromethoxyphenyl)-4-phenylthiazole-5-carboxylate (CAS 1965304-81-7)
Recommended Standards
- 2,2,2-Trifluoro-1-(2-methoxynaphthalen-1-yl)ethan-1-one (CAS 169295-61-8)
- Dimethyl 2-(3-nitropyridin-2-yl)malonate (CAS 173417-34-0)
- 2,2,2-Trifluoro-1-(4-Methoxy-naphthalen-1-yl)-ethanone (CAS 169295-54-9)
- Methyl 5-carbamoyl-2-methoxy-4-nitrobenzoate (CAS 1841081-52-4)
- Boc-D-Nva-OH (CAS 57521-85-4)
- 1,3-Dihydrofuro[3,4-c]pyridine hydrochloride (CAS 2139294-73-6)
- 2-Methoxy-4-(piperidin-4-ylmethoxy)pyridine hydrochloride (CAS 2680616-02-6)
- tert-butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate (CAS 1936077-76-7)
- Ethyl 8-bromo-6-cyano-4-hydroxyquinoline-3-carboxylate (CAS 1233518-56-3)
- 66232-90-4 Oxo(dipentyl)phenyl-lambda~5~-phosphane DTXSID30740765 (CAS 66232-90-4)
- Methyl 4-methylpent-2-ynoate (CAS 80866-47-3)
- 1-(4-Fluorophenyl)piperidin-4-amine (CAS 164721-12-4)
- 3-(trifluoromethyl)-1,4-thiazepane (CAS 1462361-43-8)
- MLCK inhibitor peptide 18 (CAS 224579-74-2)
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