8-chloro-2-methylimidazo[1,2-a]pyridine CAS 173159-42-7

Purity 97%+In StockPharmaceutical Standards
CAS No.173159-42-7
Molecular FormulaC8H15ClN2
Molecular Weight174.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-chloro-2-methylimidazo[1,2-a]pyridine CAS 173159-42-7 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 8-chloro-2-methylimidazo[1,2-a]pyridine (CAS 173159-42-7), a certified reference material (molecular formula C8H15ClN2, MW 174.67 g/mol) for analytical method development and quality control.

The molecular framework of 8-chloro-2-methylimidazo[1,2-a]pyridine (C8H15ClN2) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H15ClN2
Molecular Weight174.67 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)2006
Halogen ContentCl-containing
Nitrogen Atoms2

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