4-Methylbenzo[b]thiophene-2-carboxylic acid CAS 1735-13-3
| CAS No. | 1735-13-3 |
| Molecular Formula | C10H8O2S |
| Molecular Weight | 192.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Methylbenzo[b]thiophene-2-carboxylic acid (CAS 1735-13-3), a certified reference material (molecular formula C10H8O2S, MW 192.23 g/mol) for analytical method development and quality control.
The molecular framework of 4-Methylbenzo[b]thiophene-2-carboxylic acid (C10H8O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8O2S |
| Molecular Weight | 192.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 1 |
Related Methylbenzo Standards
- 6-Methylbenzo[b]thiophene-2-carboxylic acid (CAS 1467-86-3)
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- 4-Methylbenzo[b]thiophene-5-carboxylic acid (CAS 1547060-42-3)
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Recommended Standards
- 2-(1,1-Dioxidotetrahydrothiophen-3-yl)propanoic acid (CAS 17236-06-5)
- 2-Methyl-1-benzothiophene-3-carboxylic acid (CAS 17375-82-5)
- Methyl 2-(1,1-dioxothiolan-3-yl)acetate (CAS 17133-70-9)
- Benzothiophene-5-acetic Acid (CAS 17381-54-3)
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- 5'-Fluoro-2'-hydroxy-4-methylchalcone (CAS 850799-77-8)
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- tert-Butyl (S)-2-(hydroxymethyl)aziridine-1-carboxylate (CAS 1198080-11-3)
- 2-Amino-6-chloro-5-fluoro-3-pyridinecarbonitrile (CAS 1820711-14-5)
- 2-(Bromomethyl)-5-(difluoromethoxy)benzo[d]oxazole (CAS 1805083-22-0)
- 1-(4-bromo-3-chloro-2-fluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 1695359-94-4)
- 3-(2,4-Dichlorophenyl)-N-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 477853-44-4)
- 2-(2,4-Dichlorophenyl)propanoic acid (CAS 25173-21-1)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
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