2,2'-(1,2-Phenylene)bis(ethan-1-ol) CAS 17378-99-3
| CAS No. | 17378-99-3 |
| Molecular Formula | C10H14O2 |
| Molecular Weight | 166.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2'-(1,2-Phenylene)bis(ethan-1-ol).
2,2'-(1,2-Phenylene)bis(ethan-1-ol) (CAS 17378-99-3) is a high-purity analytical reference standard with the molecular formula C10H14O2 and a molecular weight of 166.22 g/mol.
The molecular framework of 2,2'-(1,2-Phenylene)bis(ethan-1-ol) (C10H14O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2'-(1,2-Phenylene)bis(ethan-1-ol) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14O2 |
| Molecular Weight | 166.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Phenylene Standards
- 1,1'-(1,2-Phenylene)diethanol (CAS 68850-07-7)
- 1,1'-(1,4-Phenylene)bis(ethan-1-ol) (CAS 6781-43-7)
- 2,2'-(1,4-Phenylene)diethanamine (CAS 7423-50-9)
- 1,3-Phenylene Dicyanate (CAS 1129-88-0)
- 1,2-Phenylene Phosphorochloridite (technical grade) (CAS 1641-40-3)
- 2,2'-(1,3-Phenylene)diacetonitrile (CAS 626-22-2)
- (2-Methyl-1,4-phenylene)diboronic acid (CAS 1207729-79-0)
- (3-methyl-1,2-phenylene)dimethanol (CAS 90534-48-8)
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- N-Benzoyl-N-phenylpiperidine-1-carboxamide (CAS 391861-28-2)
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