4-(1-Pyrrolidinylmethyl)-1,3-thiazol-2-ylamine CAS 17386-09-3
| CAS No. | 17386-09-3 |
| Molecular Formula | C8H13N3S |
| Molecular Weight | 183.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(1-Pyrrolidinylmethyl)-1,3-thiazol-2-ylamine (C8H13N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(1-Pyrrolidinylmethyl)-1,3-thiazol-2-ylamine (CAS 17386-09-3), molecular formula C8H13N3S and molecular weight 183.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(1-Pyrrolidinylmethyl)-1,3-thiazol-2-ylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13N3S |
| Molecular Weight | 183.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pyrrolidinylmethyl Standards
- 4-Methyl-1-(2-pyrrolidinylmethyl)piperidinedihydrochloride (CAS 1220027-22-4)
- 2-MEthyl-1-(2-pyrrolidinylmethyl)piperidine (CAS 881041-19-6)
- 3-(1-Pyrrolidinylmethyl)benzonitrile (CAS 321198-27-0)
- 100158-63-2 2-(1-pyrrolidinylmethyl)-piperidine 2-(1-pyrrolidinylmethyl)piperidine 2-(pyrrolidin-1-ylmethyl)piperidine 2-Pyrrolidin-1-ylmethyl-piperidine (CAS 100158-63-2)
- 4-(1-Pyrrolidinylmethyl)piperidine (CAS 683772-11-4)
- 1-Methyl-4-(3-pyrrolidinylmethyl)-1H-pyrazole (CAS 1339153-35-3)
- (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine (S)-1-(pyrrolidin-2-ylmethyl)pyrrolidine 51207-66-0 A7566 (CAS 51207-66-0)
- 2-(1-Pyrrolidinylmethyl)-1h-pyrrole (CAS 56162-74-4)
Recommended Standards
- 4-(Methoxymethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (CAS 1707403-01-7)
- 1-(thian-4-yl)-1H-pyrazol-3-amine (CAS 1781538-18-8)
- 2-((Azetidin-3-ylmethyl)thio)-1-methyl-1H-imidazole (CAS 1706435-92-8)
- 6'-fluorospiro[azetidine-3,1'-indane] (CAS 1782046-47-2)
- 2-Chloro-3-(4-isopropylpiperazin-1-yl)pyrazine (CAS 651047-53-9)
- 4-[4-(4-Methoxyphenyl)pyrimidin-2-yl]phenyl 4-methoxybenzene-1-sulfonate (CAS 477856-97-6)
- H-Asp(OtBu)-AMC (CAS 149231-64-1)
- Eperisone Impurity 44 (CAS 288583-70-0)
- N-(thietan-3-yl)benzo[d]thiazol-6-amine (CAS 1873527-23-1)
- 4-(3-(Ethoxycarbonyl)-2,5-dimethyl-1H-pyrrol-1-yl)benzoic acid (CAS 500728-32-5)
- (2-Imino-1,3-thiazolidin-3-yl)acetic acid hydrobromide (CAS 479192-80-8)
- 4-Methoxyacetophenone-d (CAS 1092970-51-8)
- 3-Chloro-5,6-dimethylpyridazine-4-carboxamide (CAS 1019117-07-7)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
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