5-(4-Hydroxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione CAS 17474-27-0
| CAS No. | 17474-27-0 |
| Molecular Formula | C13H12O5 |
| Molecular Weight | 248.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(4-Hydroxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 17474-27-0), molecular formula C13H12O5 and molecular weight 248.23 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(4-Hydroxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (C13H12O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 248.23 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12O5 |
| Molecular Weight | 248.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Hydroxybenzylidene Standards
- 5-(3-Hydroxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 15795-58-1)
- 2-(2-hydroxybenzylidene)indane-1,3-dione (CAS 25299-18-7)
- 2-(2-(2-Hydroxybenzylidene)hydrazinyl)-6-methylpyrimidin-4-ol (CAS 66680-03-3)
- 2-(2-(4-Hydroxybenzylidene)hydrazinyl)-6-methylpyrimidin-4-ol (CAS 91560-27-9)
- (E)-2-(4-Hydroxybenzylidene)-5-methylbenzofuran-3(2H)-one (CAS 61976-52-1)
- 5-(2-(4-Hydroxybenzylidene)hydrazineyl)-2-methyloxazole-4-carbonitrile (CAS 620586-59-6)
- N'-(2-Hydroxybenzylidene)isonicotinohydrazide (CAS 495-84-1)
- 4-((2-Hydroxybenzylidene)amino)benzoic acid (CAS 788-24-9)
Recommended Standards
- Ethyl 8-methoxy-2-oxo-2H-chromene-3-carboxylate (CAS 1729-02-8)
- Ethyl 6-(hydroxymethyl)-2-oxo-2H-chromene-3-carboxylate (CAS 176770-20-0)
- 1-(2-Methoxyethyl)-2-oxo-1,2-dihydroquinoxaline-6-carboxylic acid (CAS 1713639-25-8)
- Dimethyl 6-methyl-1H-indazole-3,5-dicarboxylate (CAS 1788041-62-2)
- 8-Methylamino-5--nitroquinolilne (CAS 152810-27-0)
- N-Methyl-N-nitrosotoluene-4-sulphonamide (CAS 80-11-5)
- (R)-2,3,4,9-TETRAHYDRO-1H-PYRIDO[3,4-B]INDOLE-3-CARBOXAMIDE (CAS 89013-95-6)
- Valproate impurity 88 (CAS CATO-C4X-116688)
- n-((4-Bromothiophen-2-yl)methyl)-2-methylpyridin-3-amine (CAS 1504948-95-1)
- Polymyxin Impurity 22 (CAS CATO-C4X-225522)
- Rivaroxaban Impurity 181 (CAS CATO-C4X-1090181)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbonyl)cyclopropane-1-carboxylic acid (CAS 1023559-02-5)
- (1-(3-Ethylbenzofuran-2-yl)ethyl)hydrazine (CAS 1016526-47-8)
- Mitogenic Pentapeptide (CAS 87173-03-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com