| CAS No. | 175135-18-9 |
| Molecular Formula | C8H4ClF3N2S |
| Molecular Weight | 252.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
CATO manufactures 4-Chloro-6-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazole-2-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-Chloro-6-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazole-2-thione (CAS 175135-18-9), molecular formula C8H4ClF3N2S and molecular weight 252.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-6-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazole-2-thione (C8H4ClF3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
| Molecular Formula | C8H4ClF3N2S |
| Molecular Weight | 252.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |