5-(2-Chloro-6-fluorophenyl)cyclohexane-1,3-dione CAS 175136-88-6
| CAS No. | 175136-88-6 |
| Molecular Formula | C12H10ClFO2 |
| Molecular Weight | 240.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-Chloro-6-fluorophenyl)cyclohexane-1,3-dione (C12H10ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-(2-Chloro-6-fluorophenyl)cyclohexane-1,3-dione (CAS 175136-88-6), molecular formula C12H10ClFO2 and molecular weight 240.66 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2-Chloro-6-fluorophenyl)cyclohexane-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClFO2 |
| Molecular Weight | 240.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-chloro-N-[(5-cyano-2-fluorophenyl)methyl]-N-methylacetamide (CAS 1178818-50-2)
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- (1-(2-Chloro-4-fluorobenzyl)-1H-pyrazol-4-yl)methanol (CAS 1342150-75-7)
- (4-Chloro-3-fluoro-5-methylfuran-2-yl)(phenyl)methanol (CAS 1443324-44-4)
- (3-Chloro-4-fluoro-5-methylfuran-2-yl)(phenyl)methanol (CAS 1443340-13-3)
- 2-Chloro-n-(2-cyanoethyl)-n-(4-fluorophenyl)acetamide (CAS 16272-47-2)
- 2-[(4-chloro-6-fluoroquinolin-8-yl)amino]ethan-1-ol (CAS 1803600-35-2)
- [5-chloro-1-(4-fluorophenyl)-3-methyl-1h-pyrazol-4-yl]methanol (CAS 926210-77-7)
Recommended Standards
- 2-(Chloromethyl)benzoyl cyanide (CAS 155380-13-5)
- 1-Chloro-2-fluoro-8-(methoxymethoxy)naphthalene (CAS 2621935-17-7)
- 2-Chloro-n-(2-cyanoethyl)-n-(2-fluorophenyl)acetamide (CAS 571149-77-4)
- 4-chloro-7-fluoro-N,N-dimethyl-1H-indole-2-carboxamide (CAS CATO-C3D-263204)
- 2-(4-Cyano-6-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1393541-33-7)
- (1-Amino-3-methylbutan-2-yl)dimethylamine (CAS 19764-61-5)
- 2-Amino-2-(2,4-dichlorophenyl)propan-1-ol (CAS 1184816-26-9)
- (S)-2-((S)-2-((S)-2-Amino-3-(phosphonooxy)propanamido)-3-methylbutanamido)propanoic acid (CAS 88169-77-1)
- 1-Methyl-5-nitro-2(1H)-pyridinone (CAS 32896-90-5)
- 1,4-Dimethyltetralin, 56% (CAS 4175-54-6)
- 4-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yl}morpholine (CAS 127710-42-3)
- 1-(3-Fluorophenyl)-4-methylcyclohexan-1-ol (CAS 1183381-44-3)
- (5-Amino-1-(3-chloro-4-fluorophenyl)-1H-pyrazol-4-yl)(o-tolyl)methanone (CAS 618092-06-1)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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