1-(3-Amino-5-(4-chlorophenyl)thiophen-2-yl)ethan-1-one CAS 175137-02-7
| CAS No. | 175137-02-7 |
| Molecular Formula | C12H10ClNOS |
| Molecular Weight | 251.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Amino-5-(4-chlorophenyl)thiophen-2-yl)ethan-1-one (CAS 175137-02-7) is a high-purity analytical reference standard with the molecular formula C12H10ClNOS and a molecular weight of 251.73 g/mol.
1-(3-Amino-5-(4-chlorophenyl)thiophen-2-yl)ethan-1-one (C12H10ClNOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-Amino-5-(4-chlorophenyl)thiophen-2-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNOS |
| Molecular Weight | 251.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- (2-Amino-5-methylthiophen-3-yl)(4-chlorophenyl)methanone (CAS 436093-32-2)
- (2-Amino-5-methylthiophen-3-yl)(2-chlorophenyl)methanone (CAS 50508-57-1)
- 2-Amino-5-(4-chlorophenyl)-6-methylpyrimidine-4(3H)-thione (CAS 13166-55-7)
- 4-Amino-2-(2-chlorobenzyl)-1,5-dimethyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1408706-30-8)
- 2-Amino-3-(7-chloro-1H-indol-3-yl)-N-methylpropanamide (CAS 2070014-71-8)
- Methyl 5-amino-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylate (CAS 121716-20-9)
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Recommended Standards
- 7-Chloro-3-(thiophen-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1710293-26-7)
- (2-((4-Chlorophenyl)thio)pyridin-3-yl)methanol (CAS 51723-83-2)
- 1-methyl-2-oxoindoline-5-sulfonyl chloride (CAS 166883-20-1)
- 4-Chloro-N-phenylbenzenesulfinamide (CAS 14934-01-1)
- 2-(Azepan-1-yl)-6-methylpyrimidin-4-ol (CAS 1189426-42-3)
- 3-(Dimethylamino)-4-hydroxybenzamide (CAS 1243456-49-6)
- 3-Fluoropropyl isopropyl carbonate (CAS 1980085-44-6)
- (S)-tert-Butyl 3-carbamoylpyrrolidine-1-carboxylate (CAS 1350834-25-1)
- 1-(3,6-Dihydroxy-2-methoxyphenyl)ethanone (CAS 33539-20-7)
- 2-[(2-Methoxyethyl)amino]acetic acid (CAS 205124-55-6)
- cis-3-(4-Methylbenzoyl)cyclopentane-1-carboxylic acid (CAS 732252-10-7)
- N-(4-oxo-1,4-dihydropyridin-3-yl)pivalamide (CAS 540497-47-0)
- 6'-Fluoro-1'H-spiro[piperidine-3,2'-quinazolin]-4'(3'H)-one (CAS 1707566-72-0)
- Peptide 431 (CAS CATO-CPTD788431)
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