5-(4-Fluorophenyl)-3-(methylthio)-1H-pyrazole CAS 175137-20-9
| CAS No. | 175137-20-9 |
| Molecular Formula | C10H9FN2S |
| Molecular Weight | 208.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(4-Fluorophenyl)-3-(methylthio)-1H-pyrazole (CAS 175137-20-9), molecular formula C10H9FN2S and molecular weight 208.26 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, 5-(4-Fluorophenyl)-3-(methylthio)-1H-pyrazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9FN2S |
| Molecular Weight | 208.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 4-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine (CAS 1087792-67-3)
- 4-(2-Fluorophenyl)-5-methylthiazol-2-ylamine (CAS 1225636-78-1)
- 4-(3-Fluorophenyl)-5-methylthiazol-2-ylamine (CAS 1225636-93-0)
- 4-(4-Fluorophenyl)-2-methylthiazol-5-amine (CAS 1247352-84-6)
- (2-(3-Fluorophenyl)thiazol-4-yl)methanamine (CAS 885280-31-9)
- (2-(4-Fluorophenyl)thiazol-4-yl)methanamine (CAS 885280-17-1)
- [4-(2-fluorophenyl)-1,3-thiazol-2-yl]methanamine (CAS 643725-18-2)
- {[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]methyl}amine (CAS 643723-43-7)
Recommended Standards
- Acridin-4-ylmethanamine (CAS 17411-38-0)
- Anthracen-2-ylhydrazine (CAS 17529-06-5)
- N-{[5-(pyrrolidin-2-yl)furan-2-yl]methyl}acetamide (CAS 1713602-56-2)
- 3-Ethoxy-4-(methylsulfonyl)-1,2,5-thiadiazole (CAS 178368-42-8)
- Methyl (2s)-2-amino-3-(2,4-difluorophenyl)propanoate hydrochloride (CAS 2416218-96-5)
- 4-(4-Methoxyphenyl)-2,6-dihydro-1,3,5-oxathiazine (CAS 58955-83-2)
- 4-(5-Chloro-3-methyl-1H-pyrazol-1-yl)phenol (CAS 1713713-62-2)
- 5-(Pyridin-2-yl)oxazol-2-amine (CAS 1014629-81-2)
- 3-(1-Benzylpiperidin-4-yl)-1-phenylurea (CAS 41220-40-0)
- 3-(2-Fluoro-4-(trifluoromethyl)phenyl)pyridine (CAS 1214382-96-3)
- Methyl 2-{[3-oxo-2-benzofuran-1(3H)-yliden]methyl}-1-hydrazinecarboxylate (CAS 320424-96-2)
- Clindamycin Impurity 74 (CAS CATO-C4X-134174)
- 2-(3,5-Difluoro-2-methoxyphenyl)acetonitrile (CAS 886761-64-4)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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