1-(4-Nitrophenyl)-5-(trifluoromethyl)pyrazole-4-carbonyl chloride CAS 175137-36-7
| CAS No. | 175137-36-7 |
| Molecular Formula | C11H5ClF3N3O3 |
| Molecular Weight | 319.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Nitrophenyl)-5-(trifluoromethyl)pyrazole-4-carbonyl chloride (CAS 175137-36-7), molecular formula C11H5ClF3N3O3 and molecular weight 319.62 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(4-Nitrophenyl)-5-(trifluoromethyl)pyrazole-4-carbonyl chloride (C11H5ClF3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 319.62 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-(4-Nitrophenyl)-5-(trifluoromethyl)pyrazole-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H5ClF3N3O3 |
| Molecular Weight | 319.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Nitrophenyl Standards
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- 5-Methyl-3-{[2-(4-nitrophenyl)-2-oxoethyl]sulfanyl}-1,2-thiazole-4-carbonitrile (CAS 343372-92-9)
- 3-Methyl-1-(4-nitrophenyl)-5-phenyl-1,4-dihydroimidazo[4,5-c]pyrazole (CAS 63330-31-4)
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- 2,2,3,3,9,9,10,10-Octamethyl-4,8-dioxa-3,9-disilaundecan-6-amine (CAS 188538-25-2)
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- Cyclopropyl Bromide (CAS 4333-56-6)
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- Talabostat (CAS 149682-77-9)
- 5-Isopropyl-2-(pyridin-4-yl)benzo[d]oxazole (CAS 1192018-77-1)
- Butyl 2,4-dichloro-6-(phenylthio)pyrimidine-5-carboxylate (CAS 87847-39-0)
- 3-(4-Fluorophenyl)-2-(5-methyl-1h-1,2,3,4-tetrazol-1-yl)propanoic acid (CAS 1118787-16-8)
- 1-(4-((2-Amino-3-nitropyridin-4-yl)oxy)-2-fluorophenyl)-3-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl)urea (CAS 1163721-32-1)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
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