5-Chloro-4-methoxy-thiophene-3-carbonyl chloride CAS 175137-49-2
| CAS No. | 175137-49-2 |
| Molecular Formula | C6H4Cl2O2S |
| Molecular Weight | 211.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chloro-4-methoxy-thiophene-3-carbonyl chloride (CAS 175137-49-2), a certified reference material (molecular formula C6H4Cl2O2S, MW 211.07 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chloro-4-methoxy-thiophene-3-carbonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-4-methoxy-thiophene-3-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4Cl2O2S |
| Molecular Weight | 211.07 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1223748-49-9 5-chloro-4-(chloromethyl)thiophene-2-carboxylic acid 5-chloro-4-(chloromethyl)thiophene-2-carboxylicacid A11405 (CAS 1223748-49-9)
- 2-Chloro-3-(chloromethyl)naphthalene (CAS 166042-74-6)
- 1-Chloro-4-(chloromethyl)naphthalene (CAS 50265-01-5)
- 7-Chloro-1-(chloromethyl)naphthalene (CAS 690223-98-4)
- 4-Chloro-5-iodo-o-xylene (CAS 1208078-25-4)
- 2-Chloro-4,5-difluorobenzoyl chloride (CAS 121872-95-5)
- 5-Chloro-2,4-difluorobenzoyl chloride (CAS 1261734-09-1)
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Recommended Standards
- Methyl 2,5-dichlorothiophene-3-carboxylate (CAS 145129-54-0)
- 5-(2-Thiazolyl)thiophene-2-boronic acid (CAS 1872434-79-1)
- 2-(3-azidopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 144266-69-3)
- 4-Bromo-2-fluorobenzyl alcohol (CAS 188582-62-9)
- 8-Methyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-ol (CAS 452323-85-2)
- 7-Chloro-3-methoxy-4-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1000575-90-5)
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- 2-(3-Formyl-1H-pyrrol-1-yl)benzonitrile (CAS 156496-63-8)
- Quininone (CAS 84-31-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com