2-[(4-chlorophenyl)methanesulfonyl]acetonitrile CAS 175137-57-2
| CAS No. | 175137-57-2 |
| Molecular Formula | C9H8ClNO2S |
| Molecular Weight | 229.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[(4-chlorophenyl)methanesulfonyl]acetonitrile.
CATO supplies 2-[(4-chlorophenyl)methanesulfonyl]acetonitrile (CAS 175137-57-2), a certified reference material (molecular formula C9H8ClNO2S, MW 229.68 g/mol) for analytical method development and quality control.
The molecular framework of 2-[(4-chlorophenyl)methanesulfonyl]acetonitrile (C9H8ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClNO2S |
| Molecular Weight | 229.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related chlorophenyl Standards
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Recommended Standards
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- 4-Cyano-2,6-dimethylbenzene-1-sulfonyl chloride (CAS 1807199-55-8)
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- 4-(Aminomethyl)-n-ethylpyridin-2-amine (CAS 858362-86-4)
- (2-Methyl-6-(pyrrolidin-1-yl)pyridin-3-yl)methanol (CAS 1355201-95-4)
- 1-(2-Methoxyphenyl)piperazine Dihydrochloride (CAS 38869-49-7)
- Bz-Phe-Val-Arg-pNA (CAS 54799-93-8)
- 4-(1-methyl-1H-1,2,4-triazol-5-yl)phenol (CAS 870535-62-9)
- 1-methyl-5-[(piperidin-3-ylmethyl)amino]piperidin-2-one dihydrochloride (CAS 1864051-75-1)
- Ethyl 1H-pyrrolo[3,2-c]pyridine-4-carboxylate (CAS 1167056-36-1)
- 4-Cyclopropoxy-2-isopropyl-N,N-dimethylpyridin-3-amine (CAS 1243360-19-1)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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