4-((4-Chlorophenyl)sulfonyl)-3-methylthiophene-2-carbonyl chloride CAS 175137-66-3
| CAS No. | 175137-66-3 |
| Molecular Formula | C12H8Cl2O3S2 |
| Molecular Weight | 335.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((4-Chlorophenyl)sulfonyl)-3-methylthiophene-2-carbonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-((4-Chlorophenyl)sulfonyl)-3-methylthiophene-2-carbonyl chloride (CAS 175137-66-3) is a high-purity analytical reference standard with the molecular formula C12H8Cl2O3S2 and a molecular weight of 335.23 g/mol.
4-((4-Chlorophenyl)sulfonyl)-3-methylthiophene-2-carbonyl chloride (C12H8Cl2O3S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((4-Chlorophenyl)sulfonyl)-3-methylthiophene-2-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2O3S2 |
| Molecular Weight | 335.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
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