3-Amino-4-((4-chlorophenyl)sulfonyl)thiophene-2-carboxylic acid CAS 175201-47-5
| CAS No. | 175201-47-5 |
| Molecular Formula | C11H8ClNO4S2 |
| Molecular Weight | 317.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Amino-4-((4-chlorophenyl)sulfonyl)thiophene-2-carboxylic acid (C11H8ClNO4S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Amino-4-((4-chlorophenyl)sulfonyl)thiophene-2-carboxylic acid (CAS 175201-47-5), molecular formula C11H8ClNO4S2 and molecular weight 317.77 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Amino-4-((4-chlorophenyl)sulfonyl)thiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO4S2 |
| Molecular Weight | 317.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Amino Standards
- Benzyl 2-(2-amino-6-chloro-9H-purin-9-yl)acetate (CAS 169287-67-6)
- 5-Amino-2-chloro-n-((1-ethylpyrrolidin-2-yl)methyl)benzenesulfonamide (CAS 923153-25-7)
- 2-Amino-8-chloro-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (CAS 2104-68-9)
- 4-Amino-3-((triisopropylsilyl)ethynyl)benzoic acid (CAS 2834081-10-4)
- (S)-2-Amino-1-(4-((benzyl(methyl)amino)methyl)piperidin-1-yl)-3-methylbutan-1-one (CAS 1354003-38-5)
- (S)-2-Amino-1-(4-((benzyl(isopropyl)amino)methyl)piperidin-1-yl)propan-1-one (CAS 1354006-63-5)
- (S)-2-Amino-N-((S)-1-benzyl-piperidin-3-yl)-N-ethyl-propionamide (CAS 1354007-36-5)
- (S)-2-Amino-N-(4-(benzyl(methyl)amino)cyclohexyl)-3-methylbutanamide (CAS 1354010-08-4)
Recommended Standards
- 3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid (CAS 171002-19-0)
- 2-(Benzylamino)-4-(4-chlorophenyl)-4-oxobutanoic acid (CAS 19672-66-3)
- 2-Chloro-4-(1-naphthyl)-6-phenyl-1,3,5-triazine (CAS 1472062-95-5)
- (10S,11S)-8-chloro-11-((methylamino)methyl)-10,11-dihydrodibenzo[b,f]oxepine-10-carboxylic acid (CAS 912355-99-8)
- Ethyl 2-(2-(2-fluorophenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate (CAS 518350-22-6)
- (E)-1-(3-bromophenyl)-N-(4H-1,2,4-triazol-4-yl)methanimine (CAS 19015-62-4)
- 2-Chloro-6-fluoroisonicotinonitrile (CAS 1807272-13-4)
- Daclatasvir Impurity 21 (CAS 1312335-97-9)
- 4-Naphthylamine-1-sulfonate sodium salt hydrate (CAS 123333-48-2)
- 2-(4-Hydroxypiperidin-1-yl)-1-(thiophen-2-yl)ethanone, 95% (CAS 1248035-93-9)
- 1-phenyl-5-pyrazolone-3-carboxylic acid (CAS 119-18-6)
- Calcitriol Impurity 8 (CAS 140710-96-9)
- 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide (CAS 1211443-61-6)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com