3-Chloro-4-(methylsulfonyl)thiophene-2-carbonyl chloride CAS 175201-87-3
| CAS No. | 175201-87-3 |
| Molecular Formula | C6H4Cl2O3S2 |
| Molecular Weight | 259.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Chloro-4-(methylsulfonyl)thiophene-2-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 3-Chloro-4-(methylsulfonyl)thiophene-2-carbonyl chloride (CAS 175201-87-3), a certified reference material (molecular formula C6H4Cl2O3S2, MW 259.13 g/mol) for analytical method development and quality control.
3-Chloro-4-(methylsulfonyl)thiophene-2-carbonyl chloride (C6H4Cl2O3S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4Cl2O3S2 |
| Molecular Weight | 259.13 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
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Recommended Standards
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- 5-Bromo-4'-chlorosalicylanilide (CAS 3679-64-9)
- 4-(oxolan-2-yl)butan-2-amine (CAS 5059-26-7)
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- Tert-butyl N-(3-cyano-4-oxo-6,7-dihydro-5H-benzothiophen-2-yl)carbamate (CAS 2891993-43-2)
- 4-(8-Fluoro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid (CAS 436811-07-3)
- (4-Fluorophenyl)(piperazin-1-yl)methanone (CAS 102391-98-0)
- 3-hydrazinyl-2-methylpropan-1-ol dihydrochloride (CAS 1803612-24-9)
- 2-(2-chloroethoxy)acetonitrile (CAS 31250-08-5)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com