5-(Isopropylsulfonyl)-2-(pyridin-2-yl)pyrimidin-4-amine CAS 175202-02-5
| CAS No. | 175202-02-5 |
| Molecular Formula | C12H14N4O2S |
| Molecular Weight | 278.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(Isopropylsulfonyl)-2-(pyridin-2-yl)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-(Isopropylsulfonyl)-2-(pyridin-2-yl)pyrimidin-4-amine (CAS 175202-02-5) is a high-purity analytical reference standard with the molecular formula C12H14N4O2S and a molecular weight of 278.33 g/mol.
The molecular framework of 5-(Isopropylsulfonyl)-2-(pyridin-2-yl)pyrimidin-4-amine (C12H14N4O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14N4O2S |
| Molecular Weight | 278.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Isopropylsulfonyl Standards
- 5-(Isopropylsulfonyl)-2-(pyridin-3-yl)pyrimidin-4-amine (CAS 175202-06-9)
- 5-(4-(Isopropylsulfonyl)phenyl)pyrazin-2-amine (CAS 1349151-81-0)
- 5-(4-(Isopropylsulfonyl)benzyl)-1,3,4-oxadiazol-2-amine (CAS 1251577-69-1)
- 4-(2-(Isopropylsulfonyl)phenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-34-9)
- 4-(Isopropylsulfonyl)benzene-1-sulfonyl chloride (CAS 1540528-87-7)
- 5-(Isopropylsulfonyl)-2-(piperidin-1-yl)pyrimidin-4-amine (CAS 175202-15-0)
- 5-(Isopropylsulfonyl)-2-(pyrrolidin-1-yl)pyrimidin-4-amine (CAS 175202-04-7)
- 5-(Isopropylsulfonyl)-2-morpholinopyrimidin-4-amine (CAS 175202-03-6)
Recommended Standards
- 4-(4-Aminophenyl)-5-(ethylsulfonyl)pyrimidin-2-amine (CAS 1710472-35-7)
- 4-(3-Aminophenyl)-5-(ethylsulfonyl)pyrimidin-2-amine (CAS 1710293-75-6)
- 2-(Naphthalene-2-sulfonyl)propanehydrazide (CAS 1797040-43-7)
- 2-((1,3-Dimethyl-4-(phenylthio)-1H-pyrazol-5-yl)oxy)acetic acid (CAS 1707568-80-6)
- 1246834-00-3 N-tert-Butoxycarbonyl 2-[(3-Methyl-1-oxo)butyl]aniline Oxime (CAS 1246834-00-3)
- 2,3-Dihydro-6-methoxy-phenalen-1-one (CAS 100621-80-5)
- 7-Chloro-2-iodothiazolo[5,4-d]pyrimidine (CAS 1909309-71-2)
- 5-(Allyloxy)-1-carbamoyl-1H-indole-3-carboxylic acid (CAS 1386456-36-5)
- N-(4-Methylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 864754-46-1)
- Posaconazole Impurity 184 (CAS CATO-C4X-1208184)
- (S)-2-Amino-2-(3,5-difluorophenyl)ethanol (CAS 1212932-15-4)
- 4-Bromo-5-ethylnaphthalen-2-ol (CAS 2763158-71-8)
- 6-(3-MEthylphenoxy)pyridin-3-ol (CAS 1822664-58-3)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
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