3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid CAS 175202-23-0
| CAS No. | 175202-23-0 |
| Molecular Formula | C9H11ClO4S3 |
| Molecular Weight | 314.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 314.83 g/mol gives 3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid (CAS 175202-23-0), molecular formula C9H11ClO4S3 and molecular weight 314.83 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid (C9H11ClO4S3) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11ClO4S3 |
| Molecular Weight | 314.83 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 3 |
Related Chloro Standards
- 4-(4-Chloro-phenyl)-1-(2,5-dimethyl-phenyl)-1H-imidazole-2-thiol (CAS 302938-49-4)
- 4-Chloro-N-cyclopropyl-N-(piperidin-4-yl)benzenesulfonamide (CAS 387350-81-4)
- 5-Chloro-1-methyl-3-phenyl-4-((phenylthio)methyl)-1H-pyrazole (CAS 318234-09-2)
- 8-[2-Chloro-4-(methylthio)phenyl]-8-oxooctanoic acid (CAS 951891-25-1)
- Ethyl 6-(2-chloro-4-(methylthio)phenyl)-6-oxohexanoate (CAS 951886-93-4)
- N-(3-Chloro-2-methylphenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-19-8)
- N-(3-Chloro-4-methylphenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-21-2)
- N-(5-Chloro-2-methylphenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-23-4)
Recommended Standards
- N-(2-chlorophenyl)-4-(4-ethylphenyl)thiazol-2-amine (CAS 1022527-31-6)
- (Z)-4-(4-Chlorophenyl)-3-ethyl-N-phenylthiazol-2(3H)-imine (CAS 398471-60-8)
- S-{[(4-Chlorophenyl)sulfanyl](difluoro)methyl} O-ethyl carbonodithioate (CAS 1563062-31-6)
- 2-((2-Chlorobenzylidene)amino)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 331962-70-0)
- Strontium perchlorate hydrate (CAS 13450-97-0)
- 5-CHLORO-3-(2-NITROVINYL)-1H-INDOLE (CAS 98993-95-4)
- (S)-2-((1-((Benzyloxy)carbonyl)pyrrolidin-3-yl)(isopropyl)amino)acetic acid (CAS 1354011-25-8)
- Clevidipine Butyrate Impurity 26 (CAS 1020718-27-7)
- 4-((Cyclopropylmethoxy)methyl)-3-fluorobenzaldehyde (CAS 1443338-54-2)
- N-((5-chlorothiophen-2-yl)methyl)-2-(pyridin-2-yl)ethan-1-amine (CAS 1021003-31-5)
- 4-[2-(Methylsulfanyl)-6-(4-phenylpiperazin-1-yl)pyrimidin-4-yl]piperazine-1-carboxamide (CAS 339017-91-3)
- tert-Butyl (2-amino-1-cyclohexylethyl)carbamate (CAS 1111598-02-7)
- Tolfenamic Acid (CAS 13710-19-5)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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