3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride CAS 175202-28-5

Purity 97%+In StockPharmaceutical Standards
CAS No.175202-28-5
Molecular FormulaC8H8Cl2O3S2
Molecular Weight287.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride CAS 175202-28-5 chemical structure

Description

The occurrence of 3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride (CAS 175202-28-5), a certified reference material (molecular formula C8H8Cl2O3S2, MW 287.18 g/mol) for analytical method development and quality control.

The molecular framework of 3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride (C8H8Cl2O3S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Chloro-4-(propane-2-sulfonyl)-thiophene-2-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H8Cl2O3S2
Molecular Weight287.18 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2007
Halogen ContentCl-containing
Sulfur Atoms2

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