2-(Methylthio)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide CAS 175203-36-8
| CAS No. | 175203-36-8 |
| Molecular Formula | C10H6F6N4OS |
| Molecular Weight | 344.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Methylthio)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 175203-36-8), a certified reference material (molecular formula C10H6F6N4OS, MW 344.24 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Methylthio)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (C10H6F6N4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6F6N4OS |
| Molecular Weight | 344.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- (2-(Methylthio)phenyl)(7-phenyl-1,4-thiazepan-4-yl)methanone (CAS 1797737-58-6)
- (3-(Methylthio)-8-azabicyclo[3.2.1]octan-8-yl)(4-(thiophen-3-yl)phenyl)methanone (CAS 1798490-96-6)
- (2-(Methylthio)phenyl)(2-(thiomorpholinomethyl)phenyl)methanone (CAS 898781-66-3)
- 3-(3-(Methylthio)-1,4-diphenyl-1H-pyrazol-5-yl)pyridine (CAS 871110-17-7)
- 3-(5-(Methylthio)-1,4-diphenyl-1H-pyrazol-3-yl)pyridine (CAS 871110-02-0)
- [(Methylthio)[[2-nitro-5-(propylthio)phenyl]amino]methylene]carbamic Acid Methyl Ester (CAS 88255-00-9)
- 2-(Methylthio)-6,8-bis(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one (CAS 1344087-74-6)
- 4-(Methylthio)-2-(2-phenoxyphenyl)pyrido[3,4-d]pyrimidine (CAS 1092460-51-9)
Recommended Standards
- Tert-butyl (2-(2-bromobenzyl)-3-hydroxypropyl)carbamate (CAS 1698197-59-9)
- tert-Butyl N-[3-bromo-2-(4-methoxyphenyl)propyl]carbamate (CAS 1909336-30-6)
- Thiazole-4-carboxylic acid [2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amide (CAS 1596338-75-8)
- 1-(Boc-amino)-3-bromo-1-(4-methoxyphenyl)propane (CAS 924818-01-9)
- 1-(2,4-Dimethyl-1,3-dioxolan-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethanone (CAS 90258-57-4)
- 1-(3-Chlorophenyl)-3-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)urea (CAS 328561-63-3)
- 2,3-Difluoro-4-iodobenzoic acid (CAS 501433-05-2)
- 3,7-Dimethyl-3,7-dihydro-2H-pyrrolo[3,4-f][1,2]thiazepine-6-carboxylic acid 1,1-dioxide (CAS 2306265-19-8)
- Ethyl 3-Amino-4-hydroxybenzoate (CAS 13052-92-1)
- 3-(((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)amino)propanenitrile (CAS 919347-58-3)
- Methyl 4-bromo-7-methoxyquinoline-6-carboxylate (CAS 2089310-53-0)
- 1,1'-(Pyrazine-2,6-diyl)diethanone (CAS 132855-06-2)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one (CAS 1219130-54-7)
- D-[Ser]11-Semaglutide (CAS CATO-CPTD788629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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