1-(3,5-Dichlorophenyl)biguanide hydrochloride CAS 175205-04-6
| CAS No. | 175205-04-6 |
| Molecular Formula | C8H9Cl2N5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3,5-Dichlorophenyl)biguanide hydrochloride (CAS 175205-04-6), molecular formula C8H9Cl2N5HCl and molecular weight 282.55 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 1-(3,5-Dichlorophenyl)biguanide hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2N5 HCl |
| Molecular Weight | 282.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Dichlorophenyl Standards
- 3-(2,5-Dichlorophenyl)propan-1-ol (CAS 1000529-99-6)
- 2-(2,4-Dichlorophenyl)-5-(4-nitrophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000571-77-6)
- 1-(2,4-Dichlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-29-1)
- 1-(3,4-Dichlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-88-5)
- 1-(3,5-Dichlorophenyl)-N,N-dimethyl-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000574-30-0)
- 2-(2,4-Dichlorophenyl)-5-(3-nitrophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000575-62-1)
- Ethyl 1-(3,5-dichlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-61-3)
- Ethyl 1-(3,4-dichlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-77-1)
Recommended Standards
- Eglumegad (CAS 176199-48-7)
- (S)-4-(3-Bromo-4-cyanophenyl)-1-(tert-butoxy-carbonyl)piperazine-2-carboxylic acid (CAS 1787141-29-0)
- 2-(5-Bromo-2-fluorophenyl)cyclopropane-1-carboxylic acid (CAS 1157561-84-6)
- 2-(3-Aminophenyl)-3,3-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid (CAS 1343453-38-2)
- 5-Ethyltetrahydrofuran-3-carbohydrazide (CAS 98428-43-4)
- 5-Bromo-1-chloro-3-fluoro-2-isopropoxybenzene (CAS 1820704-11-7)
- 5-fluoro-1-phenyl-1H-pyrazole-4-sulfonyl chloride (CAS 1700033-95-9)
- (S)-2-Amino-2-(5-methylfuran-2-yl)ethanol (CAS 1213004-35-3)
- 1-(5-Cyclopropylisoxazol-3-yl)cyclopentanecarboxylic acid (CAS 1352497-48-3)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
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