rel-(1R,2R)-2-(4-Fluorophenyl)cyclopropane-1-carboxylic acid CAS 175275-74-8
| CAS No. | 175275-74-8 |
| Molecular Formula | C10H9FO2 |
| Molecular Weight | 180.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), rel-(1R,2R)-2-(4-Fluorophenyl)cyclopropane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
rel-(1R,2R)-2-(4-Fluorophenyl)cyclopropane-1-carboxylic acid (CAS 175275-74-8) is a high-purity analytical reference standard with the molecular formula C10H9FO2 and a molecular weight of 180.18 g/mol.
rel-(1R,2R)-2-(4-Fluorophenyl)cyclopropane-1-carboxylic acid (C10H9FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9FO2 |
| Molecular Weight | 180.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
Recommended Standards
- trans-2-(3-Fluorophenyl)cyclopropanecarboxylic Acid (CAS 175168-72-6)
- 4-(Allyloxy)-3-fluorobenzaldehyde (CAS 175968-07-7)
- rel-(1R,2R)-2-(2-Fluorophenyl)cyclopropane-1-carboxylic acid (CAS 175168-71-5)
- 3-Methoxythietane-3-carboxylic acid 1,1-dioxide (CAS 1780968-16-2)
- 4-Fluoro-2-nitro-1-(4-nitrophenoxy)benzene (CAS 1285932-98-0)
- DI-Tert-butyl 2-cyanopiperazine-1,4-dicarboxylate (CAS 924964-23-8)
- 3-Oxo-N,3-diphenyl-2-(phenylsulfonyl)propanamide (CAS 23064-33-7)
- 5-Methyl-1-propyl-1H-pyrazole-4-carbaldehyde (CAS 890652-02-5)
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- 4-Iodohexahydro-2H-cyclopenta[b]furan-2,5-diol (CAS 62003-50-3)
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- Methoxydimethyl(vinyl)silane (CAS 16546-47-7)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
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