2-((3-(Trifluoromethyl)benzyl)sulfonyl)acetonitrile CAS 175276-81-0
| CAS No. | 175276-81-0 |
| Molecular Formula | C10H8F3NO2S |
| Molecular Weight | 263.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((3-(Trifluoromethyl)benzyl)sulfonyl)acetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-((3-(Trifluoromethyl)benzyl)sulfonyl)acetonitrile (CAS 175276-81-0), a certified reference material (molecular formula C10H8F3NO2S, MW 263.24 g/mol) for analytical method development and quality control.
2-((3-(Trifluoromethyl)benzyl)sulfonyl)acetonitrile (C10H8F3NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((3-(Trifluoromethyl)benzyl)sulfonyl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F3NO2S |
| Molecular Weight | 263.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 2-[4-(Trifluoromethyl)benzoyl]hydrazine-1-carbothioamide (CAS 10444-97-0)
- (2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)thiazol-4-yl)methanol (CAS 959582-07-1)
- Ethyl 7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1260243-51-3)
- 4-Methyl-2-((4-(trifluoromethyl)pyrimidin-2-yl)amino)pentan-1-ol (CAS 1333546-58-9)
- 4-(((1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)oxy)methyl)piperidine (CAS 1437481-05-4)
- 2-((2-(Trifluoromethyl)pyridin-4-yl)amino)benzonitrile (CAS 551921-68-7)
- 2-((4-(Trifluoromethyl)phenyl)amino)isonicotinonitrile (CAS 58408-95-0)
- 2-(2-(Methyl(2-(trifluoromethyl)phenyl)amino)ethoxy)ethan-1-ol (CAS 940201-49-0)
Recommended Standards
- N-(2,6-Difluorophenyl)-4-methoxybenzamide (CAS 155997-19-6)
- (1R,3S,5S)-2-(tert-butoxycarbonyl)-6,6-difluoro-2-azabicyclo[3.1.0]Hexane-3-carboxylic acid (CAS 1807940-76-6)
- 1-(4-Amino-3-Fluorophenyl)-3-(4-Fluorophenyl)Urea (CAS 1553900-92-7)
- Methyl 4-(2,5-difluorobenzyl)nicotinate (CAS 188439-71-6)
- 2-((2-Bromophenyl)thio)-1-(2,5-dimethyl-1h-pyrrol-3-yl)ethan-1-one (CAS 1011129-33-1)
- 2-(S-Cyclopentylthiomethyl)-1-bromobenzene (CAS 1309978-20-8)
- N-Methoxyisonicotinamide (CAS 83421-33-4)
- N-((4-(4-Bromophenyl)-5-((2-oxo-2-(thiazol-2-ylamino)ethyl)thio)-4H-1,2,4-triazol-3-yl)methyl)-2-fluorobenzamide (CAS 391899-00-6)
- 4-(1-Naphthylmethoxy)benzaldehyde (CAS 172932-11-5)
- Methyl n-(5-methyl-1-phenyl-1h-pyrazol-3-yl)carbamate (CAS 287176-87-8)
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-18-0)
- 3'-Deoxyadenosine 5’-Monophosphate (CAS 17434-81-0)
- 2-Bromo-9H-thioxanthene-9-one-10,10-dioxide (CAS 20077-15-0)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com