3-Chloro-5-(trifluoromethyl)pyridine-2-carbaldehyde CAS 175277-50-6
| CAS No. | 175277-50-6 |
| Molecular Formula | C7H3ClF3NO |
| Molecular Weight | 209.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Chloro-5-(trifluoromethyl)pyridine-2-carbaldehyde (CAS 175277-50-6), a certified reference material (molecular formula C7H3ClF3NO, MW 209.55 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-5-(trifluoromethyl)pyridine-2-carbaldehyde (C7H3ClF3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-5-(trifluoromethyl)pyridine-2-carbaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF3NO |
| Molecular Weight | 209.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-4-(trifluoromethyl)nicotinaldehyde (CAS 1005171-96-9)
- 3-Chloro-2,4,5-trifluorobenzamide (CAS 101513-85-3)
- 6-Chloro-4-(trifluoromethyl)pyridine-2-carboxaldehyde (CAS 1060805-47-1)
- 4-Chloro-6-(trifluoromethyl)picolinaldehyde (CAS 1060807-45-5)
- 2-Chloro-6-(trifluoromethyl)isonicotinaldehyde (CAS 1060807-47-7)
- 4-Chloro-6-(trifluoromethyl)pyridine-3-carbaldehyde (CAS 1060807-48-8)
- 3-Chloro-6-(trifluoromethyl)picolinaldehyde (CAS 1060810-27-6)
- 5-Chloro-2-(trifluoromethyl)isonicotinaldehyde (CAS 1060810-29-8)
Recommended Standards
- 2-Chloro-4-(trifluoromethyl)pyridine-3-carbaldehyde (CAS 174008-48-1)
- 4-Chloro-6-(difluoromethyl)-5-fluoronicotinaldehyde (CAS 1804665-37-9)
- 1-(6-Chloropyridin-3-yl)-2,2,2-trifluoroethanone (CAS 150698-72-9)
- 2-Chloro-3-(difluoromethyl)-5-fluoroisonicotinaldehyde (CAS 1804673-92-4)
- Alprostadil (Prostaglandin E1) Impurity 5 (PGE0) (CAS 19313-28-1)
- Ethyl 4-(1-oxoisoindolin-2-yl)benzoate (CAS 109621-43-4)
- 3-Isoprophenylboronic acid (CAS 216019-28-2)
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- 2-amino-4-methyl-1-(thiophen-2-yl)pentan-1-ol (CAS 1181447-86-8)
- (5-(2,3-Difluorophenyl)pyridin-3-yl)methanol (CAS 887974-20-1)
- 2-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid (CAS 1260383-06-9)
- 6-[(E)-2-(4-Methoxyphenyl)ethenyl]-2-(prop-2-en-1-yl)-2,3,4,5-tetrahydropyridazin-3-one (CAS 337922-97-1)
- 2-(3-Bromo-4-chlorophenyl)-4,6-diphenyl-1,3,5-triazine (CAS 2407810-32-4)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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