4-Amino-3-(trifluoromethoxy)benzonitrile CAS 175278-23-6
| CAS No. | 175278-23-6 |
| Molecular Formula | C8H5F3N2O |
| Molecular Weight | 202.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Amino-3-(trifluoromethoxy)benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Amino-3-(trifluoromethoxy)benzonitrile (CAS 175278-23-6) is a high-purity analytical reference standard with the molecular formula C8H5F3N2O and a molecular weight of 202.13 g/mol.
Based on its molecular formula C8H5F3N2O, 4-Amino-3-(trifluoromethoxy)benzonitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 202.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N2O |
| Molecular Weight | 202.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-5-hydroxy-2-(trifluoromethyl)benzonitrile (CAS 1131623-15-8)
- 3-Amino-4-(trifluoromethoxy)benzonitrile (CAS 1220630-86-3)
- 2-Amino-4-(trifluoromethoxy)benzonitrile (CAS 1260847-67-3)
- 5-Amino-2-(trifluoromethoxy)benzonitrile (CAS 1261523-71-0)
- 2-Amino-3-(trifluoromethoxy)benzonitrile (CAS 1261581-55-8)
- 2-amino-6-(trifluoromethoxy)benzonitrile (CAS 1261861-80-6)
- 3-Amino-5-(trifluoromethoxy)benzonitrile (CAS 1261873-36-2)
- 2-Amino-5-fluoro-5-(trifluoromethyl)thiazol-4(5h)-one (CAS 13973-15-4)
Recommended Standards
- 2-(2,2,2-Trifluoroethoxy)nicotinonitrile (CAS 175277-89-1)
- 8-(Trifluoromethyl)imidazo[1,5-a]pyridin-3(2H)-one (CAS 1780804-68-3)
- 2-Oxo-2-[4-(trifluoromethyl)phenyl]acetaldehyde (CAS 1736-56-7)
- 5-(Trifluoromethyl)-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one (CAS 178393-13-0)
- 3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic Acid (CAS 176969-34-9)
- (5R,6S)-5-Fluoro-6-methoxydihydropyrimidine-2,4(1H,3H)-dione (CAS 154121-06-9)
- (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrothiophene-3,4-diol (CAS 2500-80-3)
- 2-(2-(2-(4-Bromophenoxy)acetyl)hydrazine-1-carbonyl)benzoic acid (CAS 355809-53-9)
- 2-(2-Bromo-4-chlorophenoxy)ethane-1-sulfonyl chloride (CAS 1341782-43-1)
- 3-Amino-1-(2-(3-methoxypyrrolidin-1-yl)ethyl)pyridin-2(1H)-one (CAS 2171110-41-9)
- 2-Bromo-1-ethyl-3-methylbenzene (CAS 65232-55-5)
- 3-(4-aminophenoxy)propanoic acid (CAS 350699-65-9)
- Guaiacin (CAS 36531-08-5)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
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