(E)-3-(3-nitro-4-(pyridin-2-ylthio)phenyl)acrylic acid CAS 175278-56-5
| CAS No. | 175278-56-5 |
| Molecular Formula | C14H10N2O4S |
| Molecular Weight | 302.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-3-(3-nitro-4-(pyridin-2-ylthio)phenyl)acrylic acid (CAS 175278-56-5), molecular formula C14H10N2O4S and molecular weight 302.31 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (E)-3-(3-nitro-4-(pyridin-2-ylthio)phenyl)acrylic acid (C14H10N2O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 302.31 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10N2O4S |
| Molecular Weight | 302.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related E Standards
- 3-Nitro-1-(phenylsulfonyl)-1H-indole (CAS 116325-19-0)
- 5-Nitro-1-(phenylsulfonyl)-1H-indole (CAS 124400-51-7)
- 4-Nitro-1-(phenylsulfonyl)-1H-indole (CAS 850655-62-8)
- 4-Nitro-5-(trifluoromethyl)-2-((trimethylsilyl)ethynyl)aniline (CAS 1186405-13-9)
- 5-Nitro-2-(4-(trifluoromethyl)piperidin-1-yl)benzaldehyde (CAS 1033463-37-4)
- 5-Nitro-2-((2,2,6,6-tetramethylpiperidin-4-yl)amino)benzonitrile (CAS 945367-14-6)
- 5-Nitro-2-(2-(trifluoromethyl)phenyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1708250-34-3)
- 1-Methyl-5-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1313760-71-2)
Recommended Standards
- 1-((2-Nitrophenyl)sulfonyl)-1H-indole (CAS 173908-24-2)
- ethyl 4-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-1,3-thiazole-2-carboxylate (CAS 1803589-99-2)
- 2-((6-(1H-Pyrazol-1-yl)pyridazin-3-yl)oxy)-N-(thiazol-2-yl)acetamide (CAS 1428351-54-5)
- 1-(Benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 189089-90-5)
- 5-Bromo-1-ethyl-4-methyl-1H-imidazole (CAS 1856030-55-1)
- 6-(2,3-Dimethylphenoxy)-N-(2-oxotetrahydrothiophen-3-yl)nicotinamide (CAS 321521-93-1)
- 1H-Imidazol-2-ylmethanol;hydrochloride (CAS 116177-22-1)
- 4-Amino-2-chloro-3-methylphenol hydrochloride (CAS 1998216-20-8)
- Pazopanib Impurity 35 (CAS CATO-C4X-172535)
- (±)-ORG 28611 (CAS 784138-08-5)
- 6-(Benzyloxy)-2-methylpyridin-3-amine (CAS 1134328-00-9)
- 4-Bromo-2-((methoxymethoxy)methyl)-1-(trifluoromethoxy)benzene (CAS 1623766-71-1)
- n-(Piperidin-4-yl)cyclopropanesulfonamide (CAS 1203171-87-2)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
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