4-(Trifluoromethyl)benzamidine hydrochloride dihydrate CAS 175278-62-3
| CAS No. | 175278-62-3 |
| Molecular Formula | C8H7F3N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(Trifluoromethyl)benzamidine hydrochloride dihydrate (CAS 175278-62-3), a certified reference material (molecular formula C8H7F3N2HClH2O, MW 242.62 g/mol) for analytical method development and quality control.
The molecular framework of 4-(Trifluoromethyl)benzamidine hydrochloride dihydrate (C8H7F3N2HClH2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Trifluoromethyl)benzamidine hydrochloride dihydrate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F3N2 HCl 2*H2O |
| Molecular Weight | 242.62 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- Ethyl 2-amino-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylate (CAS 729608-50-8)
- 4-((1-Methylpiperidin-4-yl)amino)butan-1-ol (CAS 1247828-04-1)
- Sodium 3-chloro-4-methoxybenzenesulfinate (CAS 196866-01-0)
- Ethyl 8-bromo-5,6-dihydro-4H-benzo[6,7]cyclohepta[1,2-d]thiazole-2-carboxylate (CAS 1956310-95-4)
- 1-(3,4-Dimethylphenyl)-3-(ethoxycarbonyl)-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264048-16-9)
- N-((5-((2-(Benzo[d]thiazol-2-ylamino)-2-oxoethyl)thio)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)methyl)-2-fluorobenzamide (CAS 391899-60-8)
- 3-Amino-6-methylpyridazine-4-carboxylic acid (CAS 20886-75-3)
- 4-Hydroxy-3-methoxyphenyl Acetate (CAS 57244-88-9)
- 1-((3-Bromo-4-fluorophenyl)sulfonyl)-4-methylpiperidine (CAS 1704097-06-2)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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