Fmoc-α-amino-DL-Gly(Boc)-OH CAS 176039-39-7
| CAS No. | 176039-39-7 |
| Molecular Formula | C22H24N2O6 |
| Molecular Weight | 412.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fmoc-α-amino-DL-Gly(Boc)-OH.
CATO supplies Fmoc-α-amino-DL-Gly(Boc)-OH (CAS 176039-39-7), a certified reference material (molecular formula C22H24N2O6, MW 412.44 g/mol) for analytical method development and quality control.
Fmoc-α-amino-DL-Gly(Boc)-OH (C22H24N2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O6 |
| Molecular Weight | 412.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Related Fmoc Standards
- (R)-Fmoc-β-Phe(3-CN)-OH (CAS 517905-91-8)
- (S)-Fmoc-β-Phe(3-CN)-OH (CAS 507472-23-3)
- Fmoc-2-cyano-D-phenylalanine (CAS 401620-74-4)
- Fmoc-2-cyano-L-phenylalanine (CAS 401933-16-2)
- Fmoc-3-cyano-D-phenylalanine (CAS 205526-37-0)
- Fmoc-3-cyano-L-phenylalanine (CAS 205526-36-9)
- Fmoc-a-amino-D-Gly(Boc)-OH (B-3585.0500) (CAS 306773-83-1)
- Fmoc-4-cyano-Phe-OH (CAS 173963-93-4)
Recommended Standards
- Boc-D-Asn(Xan)-OH (CAS 200192-48-9)
- Boc-Asn(Xan)-OH (CAS 65420-40-8)
- (SP-4-2)-Trichloro(4-methoxypyridine-κN)gold (CAS 1089100-76-4)
- Enarodustat Impurity 2 (CAS CATO-C4X-32282)
- sodium 2-[2-(hydroxymethyl)phenyl]acetate (CAS 262603-24-7)
- N-(3-Amino-4-fluorophenyl)cyclopentanecarboxamide (CAS 926255-16-5)
- Platinum,bis(L-ascorbato-O3)(1,2-cyclohexanediamine-N,N')- (CAS 92784-30-0)
- Hex-1-yn-3-ol (CAS 105-31-7)
- 5-methoxypyrazolo[1,5-a]pyridine-2-carboxylic acid (CAS 876379-71-4)
- 1-(4-(Benzofuran-2-yl)thiazol-2-yl)-3-(thiophen-2-yl)urea (CAS 1206988-80-8)
- 6-(2,5-Dimethoxyphenyl)-2-(2-methylbenzyl)pyridazin-3(2H)-one (CAS 923091-47-8)
- 2-(3-Bromo-4-(trifluoromethoxy)phenyl)acetic acid (CAS 2169367-08-0)
- 1-Bromo-3,4-difluoro-2,5-dimethoxybenzene (CAS 2432848-66-1)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
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