4-Chloro-2-methyl-5-(methylsulfonyl)-benzoic Acid CAS 176309-00-5
| CAS No. | 176309-00-5 |
| Molecular Formula | C9H9ClO4S |
| Molecular Weight | 248.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-2-methyl-5-(methylsulfonyl)-benzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Chloro-2-methyl-5-(methylsulfonyl)-benzoic Acid (CAS 176309-00-5) is a high-purity analytical reference standard with the molecular formula C9H9ClO4S and a molecular weight of 248.68 g/mol.
4-Chloro-2-methyl-5-(methylsulfonyl)-benzoic Acid (C9H9ClO4S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO4S |
| Molecular Weight | 248.68 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-3-methyl-4-(methylsulfonyl)benzoic acid (CAS 106904-09-0)
- 2-(3-Chloro-4-(methylsulfonyl)phenyl)acetic acid (CAS 1265819-83-7)
- 4-Chloro-2-cyclopropyl-6-(4-fluorophenyl)pyrimidine (CAS 1354753-95-9)
- 5-chloro-2-(ethanesulfonyl)benzoic acid (CAS 1384428-08-3)
- Methyl 2-chloro-5-(methylsulfonyl)benzoate (CAS 151104-30-2)
- Methyl 3-chloro-5-(methylsulfonyl)benzoate (CAS 151104-62-0)
- 1-(3-Chloro-4-fluorophenyl)-2-phenylethan-1-one (CAS 845781-19-3)
- 1-(3-Chloro-5-fluorophenyl)-2-phenylethan-1-one (CAS 845781-21-7)
Recommended Standards
- Methyl 3-((chlorosulfonyl)methyl)benzoate (CAS 174961-63-8)
- [4-(Chlorosulfonyl)phenyl]methyl acetate (CAS 190711-51-4)
- 3-(Allyloxy)-4-chloro-5-methoxythiophene-2-carboxylic acid (CAS 1707391-82-9)
- (2-Chlorophenyl)(3-fluoro-4-methylphenyl)methanone (CAS 951886-15-0)
- (1R,3r)-3-(3,5-difluoro-4-(trifluoromethoxy)phenoxy)cyclobutan-1-amine hydrochloride (CAS 1638767-90-4)
- 1H-Benzo[d]imidazole-1-carbaldehyde (CAS 90196-39-7)
- 1-(1-Aminopropan-2-yl)-2,3-dimethylcyclohexan-1-ol (CAS 1559372-64-3)
- 5-((4-Chlorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318239-39-3)
- trans-3-Oxabicyclo[3.1.0]hexane-6-methanol (CAS 135577-15-0)
- Imidazo[1,2-b]pyridazine-8-carboxylic acid (CAS 1159977-66-8)
- 7-(1-Methylethyl)-1H-indole-2,3-dione (CAS 57816-97-4)
- 3-(3-Phenylacryloyl)-2H-chromen-2-one (CAS 76011-67-1)
- 2-(Pyridin-2-yl)-1H-indole-3-carbaldehyde hydrochloride (CAS 1049753-09-4)
- Peptide 440 (CAS CATO-CPTD788440)
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