Aripiprazole Impurity N19 CAS 17641-08-6
| CAS No. | 17641-08-6 |
| Molecular Formula | C9H10ClNO2 |
| Molecular Weight | 199.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Aripiprazole Impurity N19 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Aripiprazole Impurity N19 (CAS 17641-08-6, C9H10ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Aripiprazole Impurity N19 (C9H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Aripiprazole Impurity N19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H10ClNO2 |
| Molecular Weight | 199.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Aripiprazole Standards
- Aripiprazole Impurity 33 (CAS 50297-40-0)
- Aripiprazole Impurity 42 (CAS CATO-C4X-100842)
- Aripiprazole Impurity 34 (CAS 39512-50-0)
- Aripiprazole Impurity 84 (CAS CATO-C4X-100884)
- Aripiprazole Impurity N16 (CAS 1260893-49-9)
- Aripiprazole Impurity 87 (CAS CATO-C4X-100887)
- Aripiprazole Impurity 28 (CAS 1359829-23-4)
- Aripiprazole Impurity 75 (CAS 1782324-31-5)
Recommended Standards
- L-2-Chlorophenylalanine (CAS 103616-89-3)
- H-4-Chloro-Phe-OH (CAS 14173-39-8)
- 2-Chloro-DL-phenylalanine (CAS 14091-11-3)
- 4-Chloro-DL-phenylalanine (CAS 7424-00-2)
- Losartan Impurity 57 (CAS C4X-13305)
- Tiapride EP Impurity A (CAS 63484-12-8)
- Rimegepant Impurity 152 (CAS CATO-C4X-2487152)
- Irinotecan Impurity 52-D5 (CAS 718612-51-2)
- 1-Cyclopropyl-2-methyl-3-(2-methylfuran-3-yl)propane-1,3-dione (CAS 1493524-14-3)
- 2-(Benzyloxy)-1,3-dibromo-5-isopropylbenzene (CAS 2379321-51-2)
- Testosterone Impurity 12 (CAS CATO-C4X-132612)
- 6-Hexachloro-Fluorescein Phosphoramidite (CAS 1360547-55-2)
- Ethyl 7-(2-chloro-4-(methylthio)phenyl)-7-oxoheptanoate (CAS 951886-97-8)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com