(1R,7AS)-1-methoxytetrahydro-1H-pyrrolizin-3(2H)-one CAS 176484-64-3

Purity 97%+In StockPharmaceutical Standards
CAS No.176484-64-3
Molecular FormulaC8H13NO2
Molecular Weight155.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(1R,7AS)-1-methoxytetrahydro-1H-pyrrolizin-3(2H)-one CAS 176484-64-3 chemical structure

Description

(1R,7AS)-1-methoxytetrahydro-1H-pyrrolizin-3(2H)-one (CAS 176484-64-3) is a high-purity analytical reference standard with the molecular formula C8H13NO2 and a molecular weight of 155.19 g/mol.

(1R,7AS)-1-methoxytetrahydro-1H-pyrrolizin-3(2H)-one (C8H13NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H13NO2
Molecular Weight155.19 g/mol
AppearanceWhite to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2007
Nitrogen Atoms1

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