(3S,4R)-rel- 3,4-Dihydroxy-D-proline CAS 17663-43-3
| CAS No. | 17663-43-3 |
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 147.13 g/mol gives (3S,4R)-rel- 3,4-Dihydroxy-D-proline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(3S,4R)-rel- 3,4-Dihydroxy-D-proline (CAS 17663-43-3), molecular formula C5H9NO4 and molecular weight 147.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3S,4R)-rel- 3,4-Dihydroxy-D-proline (C5H9NO4) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H9NO4 |
| Molecular Weight | 147.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Recommended Standards
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- Mirabegron Impurity 56 (CAS CATO-C4X-103256)
- 7-(1-methoxyethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one (CAS 2489784-54-3)
- 4-(Benzo[d][1,3]dioxol-5-yl)-3-(ethylsulfonyl)-1H-pyrazole (CAS 1707599-16-3)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
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