Dexmedetomidine Impurity 29 CAS 176721-02-1
| CAS No. | 176721-02-1 |
| Molecular Formula | C31H26N2O |
| Molecular Weight | 442.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Dexmedetomidine Impurity 29 (CAS 176721-02-1, C31H26N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dexmedetomidine Impurity 29 (C31H26N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C31H26N2O |
| Molecular Weight | 442.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Related Dexmedetomidine Standards
- Dexmedetomidine Impurity 28 (CAS 176721-01-0)
- Dexmedetomidine Impurity 30 (CAS 176721-03-2)
- Dexmedetomidine Impurity N1 (CAS 33016-47-6)
- Dexmedetomidine Impurity 12 (CAS 2240179-65-9)
- Dexmedetomidine Impurity 53 (CAS CATO-C4X-123053)
- Dexmedetomidine Impurity 60 (CAS 2700265-06-9)
- Dexmedetomidine Impurity 19 (CAS 2250243-44-6)
- Dexmedetomidine Impurity 92 (CAS CATO-C4X-123092)
Recommended Standards
- N-(3-(benzylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl)-4-(tert-butyl)benzamide (CAS 433316-64-4)
- Peramivir Impurity 129 (CAS CATO-C4X-1833129)
- Fmoc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic Acid (CAS 40761-70-4)
- Solvent Red 49 (CAS 509-34-2)
- Roxatidine Impurity 53 (CAS CATO-C4X-121353)
- Dexmedetomidine Impurity 9 (CAS 2240179-63-7)
- Nilestriol Impurity 3 (CAS CATO-C4X-24513)
- 3-(Dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 18096-70-3)
- Furazolidone Impurity 2 (CAS CATO-C4X-29012)
- N-[2-(2-methoxyphenoxy)ethyl]acetamide (CAS 293738-17-7)
- 8-Bromo-3-methoxy-6,7-dihydro-5H-benzo[7]annulen-9-yl acetate (CAS 872857-86-8)
- XMJ87I93Y9 129186-29-4 Gidazepam (1-Hydrazinocarbonyl)-7-bromo-5-phenyl-1,2-dihydro-3H-1,4-benzodiazepine-2-one UNII-XMJ87I93Y9 (CAS 129186-29-4)
- Fmoc-D-Gln(Trt)-OH (CAS 200623-62-7)
- Valosin Peptide (VQY), porcine (CAS 99510-37-9)
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