8-Bromo-2-(trifluoromethyl)quinoline CAS 176722-63-7
| CAS No. | 176722-63-7 |
| Molecular Formula | C10H5BrF3N |
| Molecular Weight | 276.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Bromo-2-(trifluoromethyl)quinoline (CAS 176722-63-7) is a high-purity analytical reference standard with the molecular formula C10H5BrF3N and a molecular weight of 276.05 g/mol.
8-Bromo-2-(trifluoromethyl)quinoline (C10H5BrF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Bromo-2-(trifluoromethyl)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5BrF3N |
| Molecular Weight | 276.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-8-(trifluoromethyl)quinoline (CAS 1059064-11-7)
- 6-Bromo-8-(trifluoromethyl)quinoline (CAS 1065074-30-7)
- 4-Bromo-6-(trifluoromethyl)quinoline (CAS 1070879-32-1)
- 2-Bromo-6-(trifluoromethyl) quinoline (CAS 1101205-26-8)
- 1-Bromo-6-(trifluoromethyl)isoquinoline (CAS 1196152-93-8)
- 3-Bromo-7-(trifluoromethyl)quinoline (CAS 1215768-16-3)
- 5-Bromo-8-(trifluoromethyl)quinoline (CAS 1239460-75-3)
- 5-Bromo-3-(trifluoromethyl)quinoline (CAS 1239462-41-9)
Recommended Standards
- 6-Fluoro-3-iodo-2-methylimidazo[1,2-a]pyridine (CAS 1669405-14-4)
- 6-Bromo-2-(trifluoromethyl)quinoline (CAS 176722-64-8)
- 3-Bromo-2-(trifluoromethyl)quinoline (CAS 1620749-79-2)
- 5-Bromo-2-(trifluoromethyl)quinoline (CAS 176722-71-7)
- tert-Butyl (4-(2-hydroxypropan-2-yl)thiazol-2-yl)carbamate (CAS 876756-13-7)
- 1-(6-Chloropyridazin-4-yl)ethan-1-one (CAS 1393585-18-6)
- 1-(3,4-Dichlorobenzyl)-5-oxo-3-pyrrolidinecarboxylic acid (CAS 919016-51-6)
- Thietane-3-carboxamide 1,1-dioxide (CAS 1785567-35-2)
- 2-(4-Chlorophenyl)-5-isopropyl-6-methylpyrimidin-4(1H)-one (CAS 61442-46-4)
- N-(6-Butyl-1,3-benzothiazol-2-yl)-3-[(2-cyanoethyl)sulfamoyl]benzamide (CAS 1090911-74-2)
- (2R)-2-(trifluoromethyl)morpholine (CAS 1393524-15-6)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 796967-48-1)
- MIL-88B(Fe) (CAS 1341134-01-7)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com