6-(Hydroxymethyl)-2-oxo-2H-chromene-3-carboxylic acid CAS 176770-22-2
| CAS No. | 176770-22-2 |
| Molecular Formula | C11H8O5 |
| Molecular Weight | 220.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-(Hydroxymethyl)-2-oxo-2H-chromene-3-carboxylic acid (CAS 176770-22-2), molecular formula C11H8O5 and molecular weight 220.18 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-(Hydroxymethyl)-2-oxo-2H-chromene-3-carboxylic acid (C11H8O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 220.18 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8O5 |
| Molecular Weight | 220.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
Related Hydroxymethyl Standards
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- 3-(Hydroxymethyl)-5-(trifluoromethoxy)benzaldehyde (CAS 2828405-70-3)
- 4-(Hydroxymethyl)-2-(trifluoromethyl)benzoic acid (CAS 481075-46-1)
- 5-(Hydroxymethyl)-2-(trifluoromethyl)benzoic acid (CAS 481075-48-3)
- Ethyl 5-(hydroxymethyl)pyrazolo[1,5-a]pyridine-3-carboxylate (CAS 1260770-97-5)
- Ethyl 6-(hydroxymethyl)imidazo[1,2-a]pyridine-2-carboxylate (CAS 135995-33-4)
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Recommended Standards
- Methyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate (CAS 174074-88-5)
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- 4-(3,5-Dioxo-1,2,4-triazolidin-4-yl)benzamide (CAS 172510-63-3)
- Methyl 2-{5,7-dioxo-5h,6h,7h-pyrrolo[3,4-b]pyridin-6-yl}acetate (CAS 178617-43-1)
- 6-(1-(2-Fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)quinoline (CAS 1025802-62-3)
- (4-Allylphenyl)(isobutyl)sulfane (CAS 1379369-66-0)
- 5-(5-Bromo-2-fluoro-3-methylphenyl)oxazole (CAS 2364584-92-7)
- 6-(Quinolin-5-yl)-1,3,5-triazine-2,4-diamine (CAS 870284-22-3)
- 2-(2-Methoxybenzyl)-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid (CAS 924827-50-9)
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