2-(Dichloromethyl)-3-methylquinazolin-4(3H)-one CAS 1772-90-3
| CAS No. | 1772-90-3 |
| Molecular Formula | C10H8Cl2N2O |
| Molecular Weight | 243.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Dichloromethyl)-3-methylquinazolin-4(3H)-one (CAS 1772-90-3) is a high-purity analytical reference standard with the molecular formula C10H8Cl2N2O and a molecular weight of 243.09 g/mol.
The molecular framework of 2-(Dichloromethyl)-3-methylquinazolin-4(3H)-one (C10H8Cl2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Dichloromethyl)-3-methylquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8Cl2N2O |
| Molecular Weight | 243.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloromethyl Standards
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- 1,4-Bis(dichloromethyl)benzene (CAS 7398-82-5)
- 1-(Dichloromethyl)-4-methylquinolin-2(1H)-one (CAS 72566-83-7)
- 4-(Dichloromethyl)-2,3,5,6-tetramethylbenzaldehyde (CAS 148990-19-6)
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Recommended Standards
- 2-(3,4-Dichlorophenyl)-5-methyl-2H-1,2,3-triazol-4-amine (CAS 1707371-52-5)
- (4-(N,N-Dimethylsulfamoyl)-3-methylphenyl)boronic acid (CAS 1778667-15-4)
- (3,5-Dimethyl-4-(N-methylsulfamoyl)phenyl)boronic acid (CAS 1704069-04-4)
- (2-(3,5-Dichlorophenyl)-1H-imidazol-5-yl)methanol (CAS 188257-68-3)
- Methyl 3-[2-(4-chloro-2-iodophenoxy)ethyl]benzoate (CAS 1924165-71-8)
- 3,5-Dibromo-4-fluorobenzylamine (CAS 1806295-05-5)
- 1-Amino-2-methyl-4-oxo-4,5-dihydro-1H-pyrrole-3-carboxylic acid (CAS 156495-76-0)
- 3,4-Difluorobenzimidamide (CAS 114040-50-5)
- 1-(2,5-Dichlorophenyl)biguanidehydrochloride (CAS 4767-32-2)
- (3S)-Isopropyl 2-(p-tolyl)pyrrolidine-3-carboxylate oxalate (CAS 1212492-92-6)
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 199192-27-3)
- 5'-((1-Oxido-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octan-4-yl)methoxy)-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid (CAS CATO-CIM-105301)
- 4-Bromo-7-iodoisoxazolo[4,5-c]pyridin-3-amine (CAS 2306261-94-7)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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